name: ER-associated misfolded protein catabolic process
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def: "The chemical reactions and pathways resulting in the breakdown of misfolded proteins transported from the endoplasmic reticulum and targeted to cytoplasmic proteasomes for degradation." [GOC:mah, GOC:vw, PMID:14607247, PMID:19520858]
comment: See also the biological process terms 'unfolded protein response ; GO:0030968' and 'retrograde protein transport, ER to cytosol ; GO:0030970'.
synonym: "endoplasmic reticulum-associated misfolded protein catabolic process" EXACT [GOC:mah]
synonym: "endoplasmic reticulum-associated misfolded protein catabolism" EXACT [GOC:mah]
synonym: "ER-associated misfolded protein breakdown" EXACT [GOC:mah]
synonym: "ER-associated misfolded protein catabolism" EXACT [GOC:mah]
synonym: "ER-associated misfolded protein degradation" EXACT [GOC:mah]
synonym: "proteasomal protein catabolism of misfolded ER proteins" EXACT [GOC:bf]
is_a: GO:0006515 ! protein quality control for misfolded or incompletely synthesized proteins
is_a: GO:0036503 ! ERAD pathway
relationship: part_of: GO:0071218 ! cellular response to misfolded protein
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