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Category:GO:0070619 ! Shc-Grb2-Sos complex
id: GO:0070619
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name: Shc-Grb2-Sos complex
namespace: cellular_component
def: "A protein complex that contains Grb2, the adaptor protein Shc and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway." [GOC:mah, PMID:7970708, PMID:8940013]
synonym: "Shc-Grb2-mSos1 complex, EGF stimulated" NARROW [CORUM:2553]
is_a: GO:0098797 ! plasma membrane protein complex
AmiGO
<GOterm>GO:0070619</GOterm>
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