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Category:GO:0070449 ! elongin complex
name: elongin complex
namespace: cellular_component
def: "A transcription elongation factor complex that suppresses RNA polymerase II pausing, and may act by promoting proper alignment of the 3'-end of nascent transcripts with the polymerase catalytic site. Consists of a transcriptionally active Elongin A subunit (about 100 kDa) and two smaller Elongin B (about 18 kDa) and Elongin C (about 15 kDa) subunits." [PMID:12676794]
comment: See also the cellular component terms 'cyclin-dependent protein kinase activating kinase holoenzyme complex ; GO:0019907' and 'DNA-directed RNA polymerase II, holoenzyme ; GO:0016591'.
synonym: "elongin (SIII) complex" EXACT [CORUM:56]
synonym: "transcription elongation factor SIII complex" EXACT [PMID:8244996]
synonym: "transcription factor B (SIII) complex" EXACT []
is_a: GO:0008023 ! transcription elongation factor complex
AmiGO
<GOterm>GO:0070449</GOterm>
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