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Category:GO:0062079 ! ATG2-ATG18 complex
name: ATG2-ATG18 complex
namespace: cellular_component
def: "A protein complex essential for autophagy during nutrient deprivation, a catabolic process that sequesters undesired cellular material into autophagosomes for delivery to lysosomes for degradation. Contributes to nutrition homeostasis and damage control in eukaryotic cells. Functions at a late step of autophagosome formation for efficient completion of sequestration, probably through facilitating recruitment of ATG8-phosphatidylethanolamine (PE) to the preautophagosomal structure (PAS) and/or its protection from deconjugation by ATG4. Composed of ATG2 and ATG18 in Saccharomyces cerevisiae." [GOC:bhm, PMID:23230146]
is_a: GO:0098796 ! membrane protein complex
relationship: part_of: GO:0034045 ! phagophore assembly site membrane
AmiGO
<GOterm>GO:0062079</GOterm>
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