Category:GO:0061542 ! 3-demethylubiquinol-n 3-O-methyltransferase activity

name: 3-demethylubiquinol-n 3-O-methyltransferase activity
namespace: molecular_function
def: "Catalysis of the reaction: S-adenosyl-L-methionine + a 3-demethylubiquinol = S-adenosyl-L-homocysteine + a ubiquinol." [GOC:dph, PMID:10777520, PMID:23190198, RHEA:44380]
comment: Note that the polyprenyl sidechain substrate for this reaction has a different number of prenyl units in different organisms (for example, ubiquinone-6 in Saccharomyces, ubiquinone- 9 in rat and ubiquinone-10 in human), and thus the natural substrate for the enzymes from different organisms has a different number of prenyl units. However, the enzyme usually shows a low degree of specificity regarding the number of prenyl units.
synonym: "2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase" NARROW []
synonym: "5-demethylubiquinone-10 methyltransferase" NARROW []
synonym: "5-demethylubiquinone-9 methyltransferase" NARROW []
synonym: "OMHMB-methyltransferase" RELATED []
synonym: "S-adenosyl-L-methionine:2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone-O-methyltransferase" RELATED []
xref: EC:2.1.1.64
xref: RHEA:44380
is_a: GO:0008171 ! O-methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
relationship: part_of: GO:0006744 ! ubiquinone biosynthetic process

AmiGO <GOterm>GO:0061542</GOterm>
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