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Category:GO:0043765 ! T/G mismatch-specific endonuclease activity
name: T/G mismatch-specific endonuclease activity
namespace: molecular_function
def: "Catalysis of the repair of T/G mismatches arising from deamination of 5-methylcytosine in DNA by nicking double-stranded DNA within the sequence CT(AT)GN or NT(AT)GG next to the mismatched thymidine residue. The incision is mismatch-dependent and strand-specific, in favor of the G-containing strand. The incision serves as a starting point for subsequent excision repair by DNA polymerase I, which excises thymidine and reinserts cytidine." [PMID:17651368]
synonym: "DNA mismatch endonuclease" BROAD []
synonym: "V.EcoKDcm" RELATED []
synonym: "very short patch repair protein" RELATED []
synonym: "Vsr mismatch endonuclease" RELATED []
is_a: GO:0004520 ! DNA endonuclease activity
AmiGO
<GOterm>GO:0043765</GOterm>
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Pages in category "GO:0043765 ! T/G mismatch-specific endonuclease activity"
The following 2 pages are in this category, out of 2 total.
