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Category:GO:0043540 ! 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex
name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex
namespace: cellular_component
def: "A homodimeric, bifunctional enzyme complex which catalyzes the synthesis and degradation of fructose 2,6-bisphosphate, and is required for both glycolysis and gluconeogenesis." [GOC:jl, GOC:so]
comment: Note that we use this single class to represent all 4 isoforms of this complex. We decided to do this because the isoforms do not differ in function, rather in expression and regulation. We may want to revisit this in future.
synonym: "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 complex" NARROW []
synonym: "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 complex" NARROW []
synonym: "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 complex" NARROW []
synonym: "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 complex" NARROW []
is_a: GO:0061695 ! transferase complex, transferring phosphorus-containing groups
relationship: part_of: GO:0005829 ! cytosol
AmiGO
<GOterm>GO:0043540</GOterm>
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Pages in category "GO:0043540 ! 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex"
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