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Category:GO:0038104 ! nodal receptor complex

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DAG for GO:0038104id: GO:0038104

name: nodal receptor complex
namespace: cellular_component
def: "A protein complex containing at least a type II activin receptor, a type I activin receptor, and a coreceptor (EGF-CFC protein) such as Cripto or Cryptic. Nodal receptor complexes are capable of binding a nodal protein and transducing the signal into the cell." [GOC:bf, GOC:signaling, PMID:11024047, PMID:15062104]
comment: Nodal signals through activin receptors but (unlike activin) also requires EGF-CFC coreceptors (such as Cripto or Cryptic in mammals) to signal. This term is intended for receptor/co-receptor components and not a nodal-receptor complex.
synonym: "ActRIIB.ALK4.EGF-CFC complex" NARROW [GOC:bf]
is_a: GO:0043235 ! receptor complex

AmiGO <GOterm>GO:0038104</GOterm>
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