name: Hedgehog signaling complex
The contents of this box are automatically generated. You can help by adding information to the "Notes"
def: "A multiprotein complex that binds microtubules in a Hedgehog-dependent manner, and is required for signal transduction by members of the Hedgehog family of proteins. The core components of the complex are the serine/threonine protein kinase Fused, the kinesin motor protein Costal2 (Cos2), and a zinc finger transcription factor (Gli family members in humans, and Cubitus interruptus (Ci) in Drosophila)." [PMID:10825151, PMID:15057936]
synonym: "Hedgehog signalling complex" EXACT 
synonym: "HSC" EXACT 
is_a: GO:0032991 ! protein-containing complex
relationship: part_of: GO:0005622 ! intracellular anatomical structure
Gene Ontology Home
See Help:References for how to manage references in GONUTS.
This category currently contains no pages or media.