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Category:GO:0033782 ! 24S-hydroxycholesterol 7-alpha-hydroxylase activity
name: 24S-hydroxycholesterol 7-alpha-hydroxylase activity
namespace: molecular_function
def: "Catalysis of the reaction: (24S)-hydroxycholesterol + O2 + reduced [NADPH-hemoprotein reductase] = (24S)-7alpha-dihydroxycholesterol + H+ + H2O + oxidized [NADPH-hemoprotein reductase]." [PMID:10748047, PMID:11013305, RHEA:46124]
synonym: "24-cholest-5-ene-3beta,24-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity" RELATED []
synonym: "24-hydroxycholesterol 7alpha-hydroxylase activity" BROAD []
synonym: "24-hydroxycholesterol 7alpha-monooxygenase activity" RELATED [EC:1.14.14.26]
xref: EC:1.14.14.26
xref: KEGG_REACTION:R07208
xref: MetaCyc:1.14.13.99-RXN
xref: RHEA:46124
is_a: GO:0008387 ! steroid 7-alpha-hydroxylase activity
is_a: GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
AmiGO
<GOterm>GO:0033782</GOterm>
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