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Category:GO:0017054 ! negative cofactor 2 complex

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DAG for GO:0017054id: GO:0017054

name: negative cofactor 2 complex
namespace: cellular_component
def: "A heterodimeric protein complex that can stably associate with TATA-binding protein on promoters, thereby preventing the assembly of transcription factors TFIIA and TFIIB and leading to repression of RNA polymerase II transcription. The two subunits, NC2alpha (Drap1) and NC2beta (Dr1), dimerize through histone fold domains of the H2A/H2B type present in the amino termini." [PMID:15574413]
is_a: GO:0090571 ! RNA polymerase II transcription repressor complex

AmiGO <GOterm>GO:0017054</GOterm>
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Pages in category "GO:0017054 ! negative cofactor 2 complex"

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