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Category:GO:0010420 ! polyprenyldihydroxybenzoate methyltransferase activity
name: polyprenyldihydroxybenzoate methyltransferase activity
namespace: molecular_function
alt_id: GO:1990886
def: "Catalysis of the reaction: a 3,4-dihydroxy-5-all-trans-polyprenylbenzoate + S-adenosyl-L-methionine = a 3-methoxy,4-hydroxy-5-all-trans-polyprenylbenzoate + S-adenosyl-L-homocysteine + H+." [PMID:10419476, PMID:23190198, PMID:9628017, RHEA:44452]
comment: Note that the polyprenyl sidechain substrate for this reaction has a different number of prenyl units in different organisms (for example, ubiquinone-6 in Saccharomyces, ubiquinone- 9 in rat and ubiquinone-10 in human), and thus the natural substrate for the enzymes from different organisms has a different number of prenyl units. However, the enzyme usually shows a low degree of specificity regarding the number of prenyl units.
synonym: "3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity" EXACT [EC:2.1.1.114]
xref: EC:2.1.1.114
xref: MetaCyc:RXN-9281
xref: RHEA:44452
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
relationship: part_of: GO:0006744 ! ubiquinone biosynthetic process
AmiGO
<GOterm>GO:0010420</GOterm>
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