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Category:GO:0009022 ! tRNA nucleotidyltransferase activity
name: tRNA nucleotidyltransferase activity
namespace: molecular_function
def: "Catalysis of the reaction: tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate." [PMID:2455297, RHEA:10628]
comment: Note that, although EC names the enzme tRNA nucleotidyltransferase, the enzyme to which this term refers is also known as 'ribonuclease PH', and degrades tRNA in the 3'-5' direction in vivo, the term does not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis It should not be confused with CCA tRNA nucleotidyltransferase..
synonym: "phosphate-dependent exonuclease activity" RELATED [EC:2.7.7.56]
synonym: "ribonuclease PH activity" RELATED [EC:2.7.7.56]
synonym: "RNase PH activity" RELATED [EC:2.7.7.56]
xref: EC:2.7.7.56
xref: MetaCyc:TRNA-NUCLEOTIDYLTRANSFERASE-RXN
xref: RHEA:10628
is_a: GO:0016779 ! nucleotidyltransferase activity
is_a: GO:0140101 ! catalytic activity, acting on a tRNA
AmiGO
<GOterm>GO:0009022</GOterm>
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Pages in category "GO:0009022 ! tRNA nucleotidyltransferase activity"
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