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Category:GO:0008349 ! MAP kinase kinase kinase kinase activity
name: MAP kinase kinase kinase kinase activity
namespace: molecular_function
def: "Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kinase kinase kinase (MAPKKK), resulting in activation of MAPKKK. MAPKKK signaling pathways relay, amplify and integrate signals from the plasma membrane to the nucleus in response to a diverse range of extracellular stimuli." [GOC:bf, PMID:11790549]
synonym: "MAP4K activity" EXACT [PMID:20811974]
synonym: "MAPKKKK" EXACT []
is_a: GO:0004674 ! protein serine/threonine kinase activity
relationship: part_of: GO:0000165 ! MAPK cascade
AmiGO
<GOterm>GO:0008349</GOterm>
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