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Category:GO:0008282 ! inward rectifying potassium channel
name: inward rectifying potassium channel
namespace: cellular_component
def: "A protein complex that comprises four pore-forming (Kir6.x) and four regulatory sulphonylurea receptor (SURx) subunits and forms a transmembrane channel through which ions may pass. The opening and closing of the channel is regulated by ATP: binding of ATP to the Kir6.x subunit inhibits channel activity, whereas binding of Mg2+-complexed ATP or ADP to the SURx subunit stimulates channel activity." [GOC:bhm, PMID:16308567, PMID:16956886]
synonym: "ATP-sensitive potassium channel complex" EXACT []
synonym: "inward rectifying K+ channel" EXACT []
synonym: "KCNJ11-SUR complex" RELATED []
synonym: "KCNJ11-SURx complex" RELATED []
synonym: "KCNJ8-SUR complex" RELATED []
synonym: "KCNJ8-SURx complex" RELATED []
synonym: "Kir6-SUR complex" RELATED []
synonym: "Kir6.1-SUR complex" RELATED []
synonym: "Kir6.1-SURx complex" RELATED []
synonym: "Kir6.2-SUR complex" RELATED []
synonym: "Kir6.2-SURx complex" RELATED []
synonym: "Kir6.x complex" RELATED []
synonym: "Kir6.x-SURx complex" RELATED []
is_a: GO:0034705 ! potassium channel complex
is_a: GO:0098797 ! plasma membrane protein complex
AmiGO
<GOterm>GO:0008282</GOterm>
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