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Category:GO:0004498 ! calcidiol 1-monooxygenase activity
name: calcidiol 1-monooxygenase activity
namespace: molecular_function
def: "Catalysis of the reaction: calcidiol + H+ + NADPH + O2 = calcitriol + H2O + NADP+." [EC:1.14.15.18, RHEA:20573]
synonym: "1-hydroxylase-25-hydroxyvitamin D3 activity" RELATED [EC:1.14.15.18]
synonym: "25-hydroxy D3-1alpha-hydroxylase activity" RELATED [EC:1.14.15.18]
synonym: "25-hydroxy vitamin D3 1-alpha-hydroxylase activity" EXACT []
synonym: "25-hydroxycholecalciferol 1-hydroxylase activity" EXACT []
synonym: "25-hydroxycholecalciferol 1-monooxygenase activity" RELATED [EC:1.14.15.18]
synonym: "25-hydroxycholecalciferol 1alpha-hydroxylase activity" RELATED [EC:1.14.15.18]
synonym: "25-hydroxycholecalciferol-1-hydroxylase activity" RELATED [EC:1.14.15.18]
synonym: "25-hydroxyvitamin D-1 alpha hydroxylase activity" RELATED [EC:1.14.15.18]
synonym: "25-hydroxyvitamin D3 1alpha-hydroxylase activity" RELATED [EC:1.14.15.18]
synonym: "25-OHD-1 alpha-hydroxylase activity" RELATED [EC:1.14.15.18]
synonym: "calcidiol,NADPH:oxygen oxidoreductase (1-hydroxylating)" EXACT []
synonym: "cytochrome P450 CYP27B" NARROW []
xref: EC:1.14.15.18
xref: KEGG_REACTION:R03610
xref: MetaCyc:CALCIDIOL-1-MONOOXYGENASE-RXN
xref: RHEA:20573
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
relationship: part_of: GO:0036378 ! calcitriol biosynthetic process from calciol
AmiGO
<GOterm>GO:0004498</GOterm>
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This category has the following 2 subcategories, out of 2 total.
Pages in category "GO:0004498 ! calcidiol 1-monooxygenase activity"
The following 2 pages are in this category, out of 2 total.
