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Category:GO:0004464 ! leukotriene-C4 synthase activity
name: leukotriene-C4 synthase activity
namespace: molecular_function
def: "Catalysis of the reaction: leukotriene C(4) = glutathione + leukotriene A(4)." [EC:4.4.1.20, RHEA:17617]
comment: Note that this function was EC:2.5.1.37.
synonym: "(7E,9E,11Z,14Z)-(5S,6R)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathione leukotriene-transferase (epoxide-ring-opening)" RELATED [EC:4.4.1.20]
synonym: "(7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate glutathione-lyase (epoxide-forming)" RELATED [EC:4.4.1.20]
synonym: "leukotriene A(4):glutathione S-leukotrienyltransferase activity" RELATED [EC:4.4.1.20]
synonym: "leukotriene A4:glutathione S-leukotrienyltransferase activity" RELATED [EC:4.4.1.20]
synonym: "leukotriene C(4) synthetase activity" RELATED [EC:4.4.1.20]
synonym: "leukotriene C4 synthetase activity" RELATED [EC:4.4.1.20]
synonym: "leukotriene-C4 glutathione-lyase (leukotriene-A4-forming)" RELATED [EC:4.4.1.20]
synonym: "LTC(4) synthase activity" RELATED [EC:4.4.1.20]
synonym: "LTC(4) synthetase activity" RELATED [EC:4.4.1.20]
synonym: "LTC4 synthase activity" RELATED [EC:4.4.1.20]
synonym: "LTC4 synthetase activity" RELATED [EC:4.4.1.20]
xref: EC:4.4.1.20
xref: KEGG_REACTION:R03059
xref: MetaCyc:LEUKOTRIENE-C4-SYNTHASE-RXN
xref: RHEA:17617
is_a: GO:0016846 ! carbon-sulfur lyase activity
AmiGO
<GOterm>GO:0004464</GOterm>
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