Category:GO:0004355 ! glutamate synthase (NADPH) activity

name: glutamate synthase (NADPH) activity
namespace: molecular_function
def: "Catalysis of the reaction: 2 L-glutamate + NADP+ = 2-oxoglutarate + L-glutamine + H+ + NADPH. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + NADP+ + H2O = NH3 + 2-oxoglutarate + NADPH + H+." [EC:1.4.1.13, RHEA:15501]
comment: Note that this term has a MetaCyc pathway reference as the pathway only has a single step.
synonym: "glutamate (reduced nicotinamide adenine dinucleotide phosphate) synthase activity" RELATED [EC:1.4.1.13]
synonym: "glutamate synthetase (NADP) activity" RELATED [EC:1.4.1.13]
synonym: "glutamine amide-2-oxoglutarate aminotransferase (oxidoreductase, NADP) activity" RELATED [EC:1.4.1.13]
synonym: "glutamine-ketoglutaric aminotransferase activity" RELATED [EC:1.4.1.13]
synonym: "GOGAT activity" BROAD [EC:1.4.1.13]
synonym: "L-glutamate synthase activity" BROAD [EC:1.4.1.13]
synonym: "L-glutamate synthetase activity" BROAD [EC:1.4.1.13]
synonym: "L-glutamate:NADP+ oxidoreductase (transaminating)" RELATED [EC:1.4.1.13]
synonym: "L-glutamine:2-oxoglutarate aminotransferase, NADPH oxidizing activity" RELATED [EC:1.4.1.13]
synonym: "NADPH GOGAT" EXACT []
synonym: "NADPH-dependent glutamate synthase activity" RELATED [EC:1.4.1.13]
synonym: "NADPH-glutamate synthase activity" RELATED [EC:1.4.1.13]
synonym: "NADPH-linked glutamate synthase" RELATED [EC:1.4.1.13]
xref: EC:1.4.1.13
xref: KEGG_REACTION:R00114
xref: MetaCyc:GLUTAMATESYN-RXN
xref: RHEA:15501
is_a: GO:0015930 ! glutamate synthase activity

AmiGO <GOterm>GO:0004355</GOterm>
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