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Category:GO:0004051 ! arachidonate 5-lipoxygenase activity
name: arachidonate 5-lipoxygenase activity
namespace: molecular_function
def: "Catalysis of the reaction: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = H2O + leukotriene A4." [RHEA:32307]
comment: Note that this is a multi-step reaction.
synonym: "5-delta-lipoxygenase activity" RELATED [EC:1.13.11.34]
synonym: "5-lipoxygenase activity" RELATED [EC:1.13.11.34]
synonym: "5Delta-lipoxygenase activity" RELATED [EC:1.13.11.34]
synonym: "arachidonate:oxygen 5-oxidoreductase activity" RELATED [EC:1.13.11.34]
synonym: "arachidonic 5-lipoxygenase activity" RELATED [EC:1.13.11.34]
synonym: "arachidonic acid 5-lipoxygenase activity" RELATED [EC:1.13.11.34]
synonym: "C-5-lipoxygenase activity" RELATED [EC:1.13.11.34]
synonym: "delta(5)-lipoxygenase activity" RELATED [EC:1.13.11.34]
synonym: "delta5-lipoxygenase activity" RELATED [EC:1.13.11.34]
synonym: "leukotriene A4 synthase" BROAD [EC:1.13.11.34]
synonym: "leukotriene-A(4) synthase activity" NARROW [EC:1.13.11.34]
synonym: "leukotriene-A4 synthase activity" RELATED [EC:1.13.11.34]
synonym: "LTA synthase activity" NARROW [EC:1.13.11.34]
xref: EC:1.13.11.34
xref: RHEA:32307
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AmiGO
<GOterm>GO:0004051</GOterm>
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