Category:GO:0001098 ! basal transcription machinery binding

name: basal transcription machinery binding
namespace: molecular_function
def: "Binding to a component of the basal transcription machinery which is composed of the RNA polymerase core enzyme and the basal transcription factor(s), the minimal set of factors required for formation of the preinitiation complex (PIC) by the RNA polymerase." [GOC:txnOH]
comment: Note that the definition of basal, or general, transcription factors has typically been done at a small number of well characterized activator-independent promoters. At an activator-dependent promoter, one or more additional factors are generally required in addition to the basal factors.
is_a: GO:0005515 ! protein binding

AmiGO <GOterm>GO:0001098</GOterm>
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