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Category:GO:0000384 ! first spliceosomal transesterification activity
name: first spliceosomal transesterification activity
namespace: molecular_function
def: "Catalysis of the first transesterification reaction of spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, while it is still joined to the 3' exon." [GOC:krc, ISBN:0879695897, PMID:19239890]
synonym: "lariat formation, 5'-splice site cleavage" RELATED []
is_a: GO:0140098 ! catalytic activity, acting on RNA
relationship: part_of: GO:0000375 ! RNA splicing, via transesterification reactions
AmiGO
<GOterm>GO:0000384</GOterm>
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Pages in category "GO:0000384 ! first spliceosomal transesterification activity"
The following 5 pages are in this category, out of 5 total.
