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CVMA5:SPIKE
Contents
| Species (Taxon ID) | Murine coronavirus (strain A59) (MHV-A59) (Murine hepatitis virus). (11142) | |
| Gene Name(s) | S | |
| Protein Name(s) | Spike glycoprotein
S glycoprotein E2 Peplomer protein Spike protein S1 90B Spike protein S2 90A | |
| External Links | ||
| UniProt | P11224 | |
| EMBL | M18379 AF029248 | |
| PIR | A27402 | |
| RefSeq | NP_045300.1 | |
| PDB | 1WDF 1WDG | |
| PDBsum | 1WDF 1WDG | |
| ProteinModelPortal | P11224 | |
| SMR | P11224 | |
| GeneID | 1489752 | |
| EvolutionaryTrace | P11224 | |
| Proteomes | UP000007192 | |
| GO | GO:0044173 GO:0016021 GO:0019031 GO:0055036 GO:0019064 GO:0009405 GO:0046813 | |
| Gene3D | 1.20.5.790 | |
| InterPro | IPR002552 IPR027400 IPR018548 | |
| Pfam | PF01601 PF09408 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0044177 |
host cell Golgi apparatus |
ECO:0000314 |
C |
Figure 7. "the S protein coaccumulated with M in the Golgi complex, although a faint reticular staining pattern was still detectable (see Fig. 7C)" |
complete | |||||
|
Colocalizes with |
GO:0044165 |
host cell endoplasmic reticulum |
ECO:0000314 |
C |
Figure 7. "a faint reticular staining pattern was still detectable (see Fig. 7C)" "As shown in Fig. 7, the reticular ER-like staining pattern of S [...]" |
complete | ||||
|
colocalizes_with |
GO:0044165 |
host cell endoplasmic reticulum |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0044177 |
host cell Golgi apparatus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0019031 |
viral envelope |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046813 |
receptor-mediated virion attachment to host cell |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0061025 |
membrane fusion |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0020002 |
host cell plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046718 |
viral entry into host cell |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009405 |
pathogenesis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019062 |
virion attachment to host cell |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0019031 |
viral envelope |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0039654 |
fusion of virus membrane with host endosome membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0039663 |
membrane fusion involved in viral entry into host cell |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0033644 |
host cell membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016032 |
viral process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0019012 |
virion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0044173 |
host cell endoplasmic reticulum-Golgi intermediate compartment membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0055036 |
virion membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 de Haan, CA et al. (1999) Mapping of the coronavirus membrane protein domains involved in interaction with the spike protein. J. Virol. 73 7441-52 PubMed GONUTS page
- ↑ Walls, AC et al. (2016) Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer. Nature 531 114-117 PubMed GONUTS page
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