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CUPNH:HMP
Contents
| Species (Taxon ID) | Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)(Ralstonia eutropha). (381666) | |
| Gene Name(s) | hmp (synonyms: fhp) | |
| Protein Name(s) | Flavohemoprotein
FHP Flavohemoglobin Hemoglobin-like protein Nitric oxide dioxygenase NO oxygenase NOD | |
| External Links | ||
| UniProt | P39662 | |
| EMBL | X74334 AY305378 | |
| PIR | A53396 | |
| RefSeq | NP_942838.1 | |
| PDB | 1CQX 3OZU 3OZV 3OZW | |
| PDBsum | 1CQX 3OZU 3OZV 3OZW | |
| ProteinModelPortal | P39662 | |
| SMR | P39662 | |
| STRING | 381666.PHG200 | |
| DrugBank | DB03147 | |
| EnsemblBacteria | AAP85952 | |
| GeneID | 2656642 | |
| KEGG | reh:PHG200 | |
| PATRIC | 35228958 | |
| eggNOG | COG1018 | |
| HOGENOM | HOG000238921 | |
| KO | K05916 | |
| OMA | SAWAQAY | |
| OrthoDB | EOG64V2BB | |
| BioCyc | CNEC381666:GJUJ-6476-MONOMER | |
| SABIO-RK | P39662 | |
| EvolutionaryTrace | P39662 | |
| Proteomes | UP000008210 | |
| GO | GO:0005737 GO:0071949 GO:0020037 GO:0005506 GO:0008941 GO:0019825 GO:0005344 GO:0051409 GO:0009636 | |
| Gene3D | 1.10.490.10 | |
| HAMAP | MF_01252 | |
| InterPro | IPR017927 IPR000971 IPR009050 IPR012292 IPR023950 IPR008333 IPR001433 IPR001221 IPR017938 | |
| Pfam | PF00970 PF00042 PF00175 | |
| PRINTS | PR00410 | |
| SUPFAM | SSF46458 SSF63380 | |
| PROSITE | PS51384 PS01033 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0008941 |
nitric oxide dioxygenase activity |
ECO:0000314 |
F |
Figure 6 shows the effects of FAD on the NOD activities of flavoHbs. This suggests dissociation and reassociation of bound FAD during enzyme turnover. |
complete | |||||
|
enables |
GO:0008941 |
nitric oxide dioxygenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008941 |
nitric oxide dioxygenase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0019825 |
oxygen binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0020037 |
heme binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0051409 |
response to nitrosative stress |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0071949 |
FAD binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008941 |
nitric oxide dioxygenase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005344 |
oxygen carrier activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000101470 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008941 |
nitric oxide dioxygenase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000101470 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0015671 |
oxygen transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000101470 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005344 |
oxygen carrier activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015671 |
oxygen transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009636 |
response to toxic substance |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Gardner, PR et al. (2000) Nitric-oxide dioxygenase activity and function of flavohemoglobins. sensitivity to nitric oxide and carbon monoxide inhibition. J. Biol. Chem. 275 31581-7 PubMed GONUTS page