GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

CUPNH:HMP

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)(Ralstonia eutropha). (381666)
Gene Name(s) hmp (synonyms: fhp)
Protein Name(s) Flavohemoprotein

FHP Flavohemoglobin Hemoglobin-like protein Nitric oxide dioxygenase NO oxygenase NOD

External Links
UniProt P39662
EMBL X74334
AY305378
PIR A53396
RefSeq NP_942838.1
PDB 1CQX
3OZU
3OZV
3OZW
PDBsum 1CQX
3OZU
3OZV
3OZW
ProteinModelPortal P39662
SMR P39662
STRING 381666.PHG200
DrugBank DB03147
EnsemblBacteria AAP85952
GeneID 2656642
KEGG reh:PHG200
PATRIC 35228958
eggNOG COG1018
HOGENOM HOG000238921
KO K05916
OMA SAWAQAY
OrthoDB EOG64V2BB
BioCyc CNEC381666:GJUJ-6476-MONOMER
SABIO-RK P39662
EvolutionaryTrace P39662
Proteomes UP000008210
GO GO:0005737
GO:0071949
GO:0020037
GO:0005506
GO:0008941
GO:0019825
GO:0005344
GO:0051409
GO:0009636
Gene3D 1.10.490.10
HAMAP MF_01252
InterPro IPR017927
IPR000971
IPR009050
IPR012292
IPR023950
IPR008333
IPR001433
IPR001221
IPR017938
Pfam PF00970
PF00042
PF00175
PRINTS PR00410
SUPFAM SSF46458
SSF63380
PROSITE PS51384
PS01033

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0008941

nitric oxide dioxygenase activity

PMID:10922365[1]

ECO:0000314

F

Figure 6 shows the effects of FAD on the NOD activities of flavoHbs. This suggests dissociation and reassociation of bound FAD during enzyme turnover.

complete
CACAO 4744

enables

GO:0008941

nitric oxide dioxygenase activity

PMID:10922365[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0008941

nitric oxide dioxygenase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR023950

F

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001433
InterPro:IPR017927

F

Seeded From UniProt

complete

enables

GO:0019825

oxygen binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012292
InterPro:IPR023950

F

Seeded From UniProt

complete

enables

GO:0020037

heme binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000971
InterPro:IPR012292
InterPro:IPR023950

F

Seeded From UniProt

complete

involved_in

GO:0051409

response to nitrosative stress

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR023950

P

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001433
InterPro:IPR017927
InterPro:IPR023950

P

Seeded From UniProt

complete

enables

GO:0071949

FAD binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR023950

F

Seeded From UniProt

complete

enables

GO:0008941

nitric oxide dioxygenase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:1.14.12.17

F

Seeded From UniProt

complete

enables

GO:0005344

oxygen carrier activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000101470

F

Seeded From UniProt

complete

enables

GO:0008941

nitric oxide dioxygenase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000101470

F

Seeded From UniProt

complete

involved_in

GO:0015671

oxygen transport

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000101470

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0005344

oxygen carrier activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0561

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

involved_in

GO:0015671

oxygen transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0561

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

involved_in

GO:0009636

response to toxic substance

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0216

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Gardner, PR et al. (2000) Nitric-oxide dioxygenase activity and function of flavohemoglobins. sensitivity to nitric oxide and carbon monoxide inhibition. J. Biol. Chem. 275 31581-7 PubMed GONUTS page