CRYNB:COX19

Species (Taxon ID)	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)(Filobasidiella neoformans). (283643)
Gene Name(s)	COX19
Protein Name(s)	Cytochrome c oxidase assembly protein COX19
External Links
UniProt	P0CM87
EMBL	AAEY01000049
RefSeq	XP_773182.1
GeneID	4938519
KEGG	cnb:CNBJ1770
KO	K18183
OrthoDB	EOG7647G0
Proteomes	UP000001435
GO	GO:0005758
InterPro	IPR010625 IPR009069
Pfam	PF06747
SUPFAM	SSF47072

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0031930	mitochondria-nucleus signaling pathway	PMID:23345593	ECO:0000315			P		COX19 is a required for the transduction of a SCO-dependent redox signal from mitochondria to ATP7A. Figure 5A-C shows the knockdown of COX19 and PET191. Knockdown of COX19 reduces cellular copper levels when compared to parental lines, whereas PET191 knockdown does not affect copper levels. COX19 is critical for regulating cellular copper efflux.	complete CACAO 9684
involved_in	GO:0033617	mitochondrial respiratory chain complex IV assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q3E731 sgd:YLL018C-A_mRNA	P		Seeded From UniProt	complete
involved_in	GO:0030001	metal ion transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q3E731 sgd:YLL018C-A_mRNA	P		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q3E731 sgd:YLL018C-A_mRNA	C		Seeded From UniProt	complete
part_of	GO:0005758	mitochondrial intermembrane space	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q3E731 sgd:YLL018C-A_mRNA	C		Seeded From UniProt	complete
enables	GO:0005507	copper ion binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q3E731 sgd:YLL018C-A_mRNA	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0496	C		Seeded From UniProt	complete
part_of	GO:0005758	mitochondrial intermembrane space	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0169	C		Seeded From UniProt	complete
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