CONMR:Q1HGL1

Species (Taxon ID)	Conus marmoreus (Marble cone). (42752)
Gene Name(s)	MrPDI (ECO:0000313 with EMBL:ABF48564.1)
Protein Name(s)	Protein disulfide-isomerase (ECO:0000256 with RuleBase:RU361130)
External Links
UniProt	Q1HGL1
EMBL	DQ486867
ProteinModelPortal	Q1HGL1
SMR	Q1HGL1
GO	GO:0005783 GO:0003756 GO:0045454
Gene3D	3.40.30.10
InterPro	IPR005788 IPR005792 IPR012336 IPR017937 IPR013766
Pfam	PF00085
SUPFAM	SSF52833
TIGRFAMs	TIGR01130 TIGR01126
PROSITE	PS00194 PS51352

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:1903332	regulation of protein folding	PMID:17697113	ECO:0000314			P		Figure 2 shows the effect of cPDI on lyzozyme refolding. At low doses, it reduces the refolding yield, but at high doses it increases the refolding yield.	complete CACAO 10913
	GO:0015035	protein disulfide oxidoreductase activity	PMID:17697113	ECO:0000314			F		Figure 4 shows the oxidation of reduced, linear tx3a in the presence of cPDI. As time progresses, the peak for the reduced form disappears and the peak for oxidized, folded tx3a appears. Panel B shows that this occurs faster with higher amounts of cPDI.	complete CACAO 10914
	GO:0016853	isomerase activity	PMID:17697113	ECO:0000314			F		Figure 6 shows the isomerization of one major refolding product of reduced Tx3.1, sTx3.1, to the normal refolding product, nTx3.1, by cPDI. As time progresses, the percentage of nTx3.1 protein increases in the presence of cPDI in a dose-dependent manner	complete CACAO 10915
enables	GO:0016853	isomerase activity	PMID:17697113	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0015035	protein disulfide oxidoreductase activity	PMID:17697113	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005623	cell	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0045454	C		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0015035	P		Seeded From UniProt	complete
enables	GO:0003756	protein disulfide isomerase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005792	F		Seeded From UniProt	complete
enables	GO:0016853	isomerase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005788	F		Seeded From UniProt	complete
involved_in	GO:0045454	cell redox homeostasis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR013766 InterPro:IPR017937	P		Seeded From UniProt	complete
enables	GO:0003756	protein disulfide isomerase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:5.3.4.1	F		Seeded From UniProt	complete
enables	GO:0016853	isomerase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0413	F		Seeded From UniProt	complete
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References

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