CLOP1:PHLC

Species (Taxon ID)	Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A). (195103)
Gene Name(s)	plc (synonyms: cpa)
Protein Name(s)	Phospholipase C PLC Alpha-toxin Hemolysin Lecithinase Phosphatidylcholine cholinephosphohydrolase
External Links
UniProt	Q0TV31
EMBL	M24904 X13608 CP000246
PIR	A30565
RefSeq	WP_011590041.1 YP_694509.1
PDB	1QM6 1QMD 2WXT 2WXU 2WY6
PDBsum	1QM6 1QMD 2WXT 2WXU 2WY6
ProteinModelPortal	Q0TV31
SMR	Q0TV31
EnsemblBacteria	ABG84486
GeneID	4201274
KEGG	cpf:CPF_0042
PATRIC	19482373
KO	K16619
OMA	DHFWDPD
OrthoDB	EOG6PS5WX
BioCyc	CPER195103:GHAW-45-MONOMER
EvolutionaryTrace	Q0TV31
Proteomes	UP000001823
GO	GO:0005576 GO:0016787 GO:0034480 GO:0008270 GO:0044179 GO:0008152 GO:0009405
Gene3D	1.10.575.10 2.60.60.20
InterPro	IPR008976 IPR001024 IPR008947 IPR001531 IPR029002
Pfam	PF01477 PF00882
PRINTS	PR00479
ProDom	PD003946
SMART	SM00770
SUPFAM	SSF48537 SSF49723
PROSITE	PS50095 PS00384 PS51346

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0016787	hydrolase activity	PMID:21704605	ECO:0000314			F		See figure 3 of paper.	complete CACAO 3347
	GO:0044179	hemolysis in other organism	PMID:21300155	ECO:0000314			P		See figure 6 in paper.	complete CACAO 3357
involved_in	GO:0044179	hemolysis in other organism	PMID:21300155	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	PMID:21704605	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0004629	phospholipase C activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001531	F		Seeded From UniProt	complete
enables	GO:0008270	zinc ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001531	F		Seeded From UniProt	complete
enables	GO:0016788	hydrolase activity, acting on ester bonds	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008947	F		Seeded From UniProt	complete
enables	GO:0004629	phospholipase C activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:3.1.4.3	F		Seeded From UniProt	complete
enables	GO:0034480	phosphatidylcholine phospholipase C activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:3.1.4.3	F		Seeded From UniProt	complete
involved_in	GO:0044179	hemolysis in other organism	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0354	P		Seeded From UniProt	complete
involved_in	GO:0009405	pathogenesis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0843	P		Seeded From UniProt	complete
involved_in	GO:0019835	cytolysis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0204	P		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
enables	GO:0090729	toxin activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0800	F		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
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References

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