CLODI:TOXA

Species (Taxon ID)	Clostridium difficile. (1496)
Gene Name(s)	toxA (synonyms: tcdA)
Protein Name(s)	Toxin A
External Links
UniProt	P16154
EMBL	X51797 M30307 X92982
PIR	A37052
PDB	2F6E 2G7C 2QJ6 3HO6 4DMV 4DMW
PDBsum	2F6E 2G7C 2QJ6 3HO6 4DMV 4DMW
ProteinModelPortal	P16154
SMR	P16154
CAZy	GT44
MEROPS	C80.002
TCDB	1.C.57.1.2
EvolutionaryTrace	P16154
GO	GO:0016757 GO:0009405
InterPro	IPR018337 IPR020974 IPR024770 IPR024772 IPR024769
Pfam	PF01473 PF11713 PF12919 PF12920 PF12918
PROSITE	PS51170

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0090044	positive regulation of tubulin deacetylation	PMID:20696758	ECO:0000314			P		Fig. 1A. Note that the GO term cannot beGO:0090042 because ToxA mediates tubulin deacetylation via HDAC6.	complete
involved_in	GO:0009405	pathogenesis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR024769	P		Seeded From UniProt	complete
enables	GO:0016757	transferase activity, transferring glycosyl groups	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR024770	F		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	P		Seeded From UniProt	complete
enables	GO:0008234	cysteine-type peptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0788	F		Seeded From UniProt	complete
involved_in	GO:0009405	pathogenesis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0260	P		Seeded From UniProt	complete
enables	GO:0008233	peptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	F		Seeded From UniProt	complete
enables	GO:0090729	toxin activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0800	F		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
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References

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