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CITFR:AMPC

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Species (Taxon ID) Citrobacter freundii. (546)
Gene Name(s) ampC (synonyms: blaC)
Protein Name(s) Beta-lactamase

Cephalosporinase

External Links
UniProt P05193
EMBL X03866
X51632
PIR S08296
PDB 1RGY
PDBsum 1RGY
ProteinModelPortal P05193
SMR P05193
BindingDB P05193
ChEMBL CHEMBL1255130
DrugBank DB00355
MEROPS S12.006
SABIO-RK P05193
EvolutionaryTrace P05193
GO GO:0030288
GO:0008800
GO:0017001
GO:0046677
Gene3D 3.40.710.10
InterPro IPR001466
IPR012338
IPR001586
Pfam PF00144
SUPFAM SSF56601
PROSITE PS00336

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0008800

beta-lactamase activity

PMID:21627834[1]

ECO:0000270

F

Beta-lactamase activity based on antibiotic susceptibility of C. freundii versus E. coli transconjugants. C. freundii shows higher MIC in most cases. See table 1.

complete
CACAO 4826

GO:0046677

response to antibiotic

PMID:21627834[1]

ECO:0000315

P

Beta-lactamase activity based on antibiotic susceptibility of C. freundii versus E. coli transconjugants. C. freundii shows higher MIC in most cases. See table 1.

complete
CACAO 4971

involved_in

GO:0046677

response to antibiotic

PMID:21627834[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0008800

beta-lactamase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001586

F

Seeded From UniProt

complete

involved_in

GO:0017001

antibiotic catabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001586

P

Seeded From UniProt

complete

part_of

GO:0030288

outer membrane-bounded periplasmic space

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001586

C

Seeded From UniProt

complete

enables

GO:0008800

beta-lactamase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.5.2.6

F

Seeded From UniProt

complete

involved_in

GO:0046677

response to antibiotic

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0046

P

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

part_of

GO:0042597

periplasmic space

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0574
UniProtKB-SubCell:SL-0200

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Millán, B et al. (2011) CTX-M-14 β-lactamase-producing Citrobacter freundii isolated in Venezuela. Ann. Clin. Microbiol. Antimicrob. 10 22 PubMed GONUTS page