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CHLRE:IFT46

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Species (Taxon ID) Chlamydomonas reinhardtii (Chlamydomonas smithii). (3055)
Gene Name(s) IFT46 (ECO:0000312 with EMBL:ABH06907.1) (synonyms: FAP32)
Protein Name(s) Intraflagellar transport protein 46

Flagellar-associated protein 32 IFT complex B protein (ECO:0000312 with EMBL:ABH06907.1)

External Links
UniProt A2T2X4
EMBL DQ787426
DS496218
RefSeq XP_001691140.1
UniGene Cre.8330
STRING 3055.JGI108954
PRIDE A2T2X4
GeneID 5716734
KEGG cre:CHLREDRAFT_108954
eggNOG NOG74258
InParanoid A2T2X4
OMA QWIASIN
Proteomes UP000006906
GO GO:0005813
GO:0097546
GO:0060170
GO:0005737
GO:0030992
GO:0031514
GO:0008022
GO:0035082
GO:0042384
GO:0044782
GO:0060285
GO:0042073
GO:0050821
GO:0015031
GO:1902017
GO:0031647
InterPro IPR022088
PANTHER PTHR13376
Pfam PF12317

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0042073

intraflagellar transport

PMID:16527740[1]

ECO:0000314

P

EM with gold labelled IFT46 antibody seen to move along flagella figure 5 and 6

complete

involved_in

GO:0050821

protein stabilization

PMID:20435895[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0060271

cilium assembly

PMID:20435895[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0042073

intraciliary transport

PMID:16527740[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0042073

intraciliary transport

PMID:20435895[2]

ECO:0000305

curator inference used in manual assertion

GO:0060271

P

Seeded From UniProt

complete

colocalizes_with

GO:0036064

ciliary basal body

PMID:20435895[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0031514

motile cilium

PMID:20435895[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0031514

motile cilium

PMID:16527740[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0030992

intraciliary transport particle B

PMID:20435895[2]

ECO:0000305

curator inference used in manual assertion

GO:0031514

C

Seeded From UniProt

complete

enables

GO:0008022

protein C-terminus binding

PMID:20435895[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q946G4

F

Seeded From UniProt

complete

part_of

GO:0030992

intraciliary transport particle B

PMID:23990561[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0042073

intraciliary transport

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000332669
UniProtKB:A2T2X4
WB:WBGene00001122

P

Seeded From UniProt

complete

part_of

GO:0030992

intraciliary transport particle B

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1923818
PANTHER:PTN000332669
UniProtKB:A2T2X4

C

Seeded From UniProt

complete

part_of

GO:0005929

cilium

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1923818
PANTHER:PTN000332669

C

Seeded From UniProt

complete

part_of

GO:0005813

centrosome

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1923818
PANTHER:PTN000332669

C

Seeded From UniProt

complete

involved_in

GO:1902017

regulation of cilium assembly

PMID:17312020[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0097546

ciliary base

PMID:17312020[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0060285

cilium-dependent cell motility

PMID:17312020[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0060170

ciliary membrane

PMID:17312020[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0044782

cilium organization

PMID:17312020[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0035082

axoneme assembly

PMID:17312020[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0031647

regulation of protein stability

PMID:17312020[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0031514

motile cilium

PMID:17312020[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0015031

protein transport

PMID:17312020[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0042073

intraciliary transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR022088

P

Seeded From UniProt

complete

part_of

GO:0030992

intraciliary transport particle B

PMID:20435895[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

part_of

GO:0042995

cell projection

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966

C

Seeded From UniProt

complete

part_of

GO:0005929

cilium

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0969
UniProtKB-SubCell:SL-0066

C

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0206

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Pedersen, LB et al. (2006) Dissecting the molecular mechanisms of intraflagellar transport in chlamydomonas. Curr. Biol. 16 450-9 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 Lucker, BF et al. (2010) Direct interactions of intraflagellar transport complex B proteins IFT88, IFT52, and IFT46. J. Biol. Chem. 285 21508-18 PubMed GONUTS page
  3. Bhogaraju, S et al. (2013) Molecular basis of tubulin transport within the cilium by IFT74 and IFT81. Science 341 1009-12 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 5.4 5.5 5.6 5.7 5.8 Hou, Y et al. (2007) Functional analysis of an individual IFT protein: IFT46 is required for transport of outer dynein arms into flagella. J. Cell Biol. 176 653-65 PubMed GONUTS page