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CHICK:VIP

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) VIP
Protein Name(s) VIP peptides

Intestinal peptide PHI-27-like Vasoactive intestinal peptide VIP Vasoactive intestinal polypeptide

External Links
UniProt P48143
EMBL U09350
X80906
PIR S47470
RefSeq NP_001170780.1
UniGene Gga.666
PaxDb P48143
Ensembl ENSGALT00000022132
GeneID 396323
KEGG gga:396323
CTD 7432
eggNOG NOG44083
GeneTree ENSGT00530000063592
HOGENOM HOG000253943
HOVERGEN HBG018069
InParanoid P48143
KO K05264
PhylomeDB P48143
Reactome REACT_246971
NextBio 20816371
PMAP-CutDB P48143
PRO PR:P48143
Proteomes UP000000539
ExpressionAtlas P48143
GO GO:0005576
GO:0010628
GO:0090277
GO:0070459
InterPro IPR000532
IPR015523
PANTHER PTHR11213:SF5
Pfam PF00123
SMART SM00070
PROSITE PS00260

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0043005

neuron projection

PMID:9629189[1]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(UBERON:0001877)|part_of:(UBERON:0002667)|part_of:(UBERON:0001929)|part_of:(UBERON:0001935)|part_of:(UBERON:0002034)|part_of:(UBERON:0002746)

Seeded From UniProt

complete

involved_in

GO:0070459

prolactin secretion

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P45644:PRO_0000011484

P

Seeded From UniProt

complete

involved_in

GO:0048255

mRNA stabilization

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P45644:PRO_0000011484

P

Seeded From UniProt

complete

involved_in

GO:0032812

positive regulation of epinephrine secretion

PMID:11927398[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0048242

epinephrine secretion

PMID:10974664[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(CL:0000166)

Seeded From UniProt

complete

involved_in

GO:0007189

adenylate cyclase-activating G protein-coupled receptor signaling pathway

PMID:12794310[4]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(UBERON:0000956)

Seeded From UniProt

complete

involved_in

GO:0097755

positive regulation of blood vessel diameter

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002598709
RGD:621647

P

Seeded From UniProt

complete

involved_in

GO:0060406

positive regulation of penile erection

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002598709
RGD:621647

P

Seeded From UniProt

complete

involved_in

GO:0051930

regulation of sensory perception of pain

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002598709
RGD:621647

P

Seeded From UniProt

complete

enables

GO:0051428

peptide hormone receptor binding

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000130195
UniProtKB:P18509

F

Seeded From UniProt

complete

involved_in

GO:0048662

negative regulation of smooth muscle cell proliferation

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002598709
RGD:621647

P

Seeded From UniProt

complete

involved_in

GO:0048242

epinephrine secretion

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002598709
UniProtKB:P48143

P

Seeded From UniProt

complete

involved_in

GO:0045732

positive regulation of protein catabolic process

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98933
PANTHER:PTN002598709
RGD:621647
UniProtKB:P01282
UniProtKB:P01284
UniProtKB:P81401

P

Seeded From UniProt

complete

involved_in

GO:0043267

negative regulation of potassium ion transport

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002598709
RGD:621647

P

Seeded From UniProt

complete

part_of

GO:0043204

perikaryon

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002598709
UniProtKB:P48143

C

Seeded From UniProt

complete

involved_in

GO:0043066

negative regulation of apoptotic process

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002598709
RGD:621647

P

Seeded From UniProt

complete

part_of

GO:0043005

neuron projection

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002598709
UniProtKB:P48143

C

Seeded From UniProt

complete

involved_in

GO:0032880

regulation of protein localization

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98933
PANTHER:PTN002598709
RGD:621647
UniProtKB:P01282
UniProtKB:P01284
UniProtKB:P81401

P

Seeded From UniProt

complete

involved_in

GO:0032812

positive regulation of epinephrine secretion

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002598709
UniProtKB:P48143

P

Seeded From UniProt

complete

involved_in

GO:0007611

learning or memory

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002598709
RGD:621647

P

Seeded From UniProt

complete

involved_in

GO:0007200

phospholipase C-activating G protein-coupled receptor signaling pathway

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002598709
ZFIN:ZDB-GENE-080204-3

P

Seeded From UniProt

complete

involved_in

GO:0007189

adenylate cyclase-activating G protein-coupled receptor signaling pathway

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:105094
MGI:MGI:95709
MGI:MGI:98933
PANTHER:PTN000130195
RGD:2037
RGD:61883
RGD:621647
UniProtKB:P01282
UniProtKB:P01284
UniProtKB:P01286
UniProtKB:P18509
UniProtKB:P41535
UniProtKB:P48143
UniProtKB:P81401
UniProtKB:Q29W19

P

Seeded From UniProt

complete

enables

GO:0005184

neuropeptide hormone activity

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000130195
RGD:2037
UniProtKB:P18509
UniProtKB:Q29W19

F

Seeded From UniProt

complete

involved_in

GO:0001938

positive regulation of endothelial cell proliferation

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002598709
RGD:621647

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005179

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005184

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005179

P

Seeded From UniProt

complete

enables

GO:0005179

hormone activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000532

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000532

C

Seeded From UniProt

complete

involved_in

GO:0070459

prolactin secretion

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P45644:PRO_0000011484

P

Seeded From UniProt

complete

involved_in

GO:0048255

mRNA stabilization

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P45644:PRO_0000011484

P

Seeded From UniProt

complete

involved_in

GO:0010467

gene expression

PMID:8536940[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0090277

positive regulation of peptide hormone secretion

PMID:8536940[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0070459

prolactin secretion

PMID:8536940[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005179

hormone activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0372

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

involved_in

GO:0090277

positive regulation of peptide hormone secretion

PMID:9845667[7]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0070459

prolactin secretion

PMID:9845667[7]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010628

positive regulation of gene expression

PMID:9845667[7]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:12535623[8]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Peeters, K et al. (1998) Comparative distribution of pituitary adenylate cyclase-activating polypeptide and vasoactive intestinal polypeptide immunoreactivity in the chicken forebrain. Ann. N. Y. Acad. Sci. 839 417-9 PubMed GONUTS page
  2. Montpetit, CJ & Perry, SF (2002) Adrenergic regulation of catecholamine secretion from trout (Oncorhynchus mykiss) chromaffin cells. J. Endocrinol. 173 187-97 PubMed GONUTS page
  3. Montpetit, CJ & Perry, SF (2000) Vasoactive intestinal polypeptide- and pituitary adenylate cyclase activating polypeptide-mediated control of catecholamine release from chromaffin tissue in the rainbow trout, Oncorhynchus mykiss. J. Endocrinol. 166 705-14 PubMed GONUTS page
  4. Nowak, JZ et al. (2003) Antagonism of VIP-stimulated cyclic AMP formation in chick brain. J. Mol. Neurosci. 20 163-72 PubMed GONUTS page
  5. 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 5.13 5.14 5.15 5.16 5.17 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  6. 6.0 6.1 6.2 Sun, S & el Halawani, ME (1995) Protein kinase-C mediates chicken vasoactive intestinal peptide stimulated prolactin secretion and gene expression in turkey primary pituitary cells. Gen. Comp. Endocrinol. 99 289-97 PubMed GONUTS page
  7. 7.0 7.1 7.2 Tong, Z et al. (1998) Vasoactive intestinal peptide stimulates turkey prolactin gene expression by increasing transcription rate and enhancing mRNA stability. J. Mol. Endocrinol. 21 259-66 PubMed GONUTS page
  8. Bhatt, R et al. (2003) Dopamine infusion into the third ventricle increases gene expression of hypothalamic vasoactive intestinal peptide and pituitary prolactin and luteinizing hormone beta subunit in the turkey. Gen. Comp. Endocrinol. 130 41-7 PubMed GONUTS page