CHICK:TPH1

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	TPH1 (synonyms: TPH)
Protein Name(s)	Tryptophan 5-hydroxylase 1 Tryptophan 5-monooxygenase 1
External Links
UniProt	P70080
EMBL	U26428
RefSeq	NP_990287.1
UniGene	Gga.43354
PDB	3E2T
PDBsum	3E2T
ProteinModelPortal	P70080
SMR	P70080
STRING	9031.ENSGALP00000010070
Ensembl	ENSGALT00000010084
GeneID	395799
KEGG	gga:395799
CTD	7166
eggNOG	COG3186
GeneTree	ENSGT00390000010268
HOGENOM	HOG000233373
HOVERGEN	HBG006841
InParanoid	P70080
KO	K00502
OMA	QNVLMYG
OrthoDB	EOG7KM5T1
PhylomeDB	P70080
TreeFam	TF313327
Reactome	REACT_252844
UniPathway	UPA00846
EvolutionaryTrace	P70080
NextBio	20815867
PRO	PR:P70080
Proteomes	UP000000539
GO	GO:0016597 GO:0005506 GO:0004510 GO:0009072 GO:0046849 GO:0042427
Gene3D	1.10.800.10
InterPro	IPR002912 IPR001273 IPR018301 IPR019774 IPR005963 IPR019773
PANTHER	PTHR11473
Pfam	PF01842 PF00351
PIRSF	PIRSF000336
PRINTS	PR00372
SUPFAM	SSF56534
TIGRFAMs	TIGR01270
PROSITE	PS51671 PS00367 PS51410

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
part_of	GO:0043005	neuron projection		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2651811 PANTHER:PTN000158467 RGD:3895 WB:WBGene00006600	C		Seeded From UniProt	complete
enables	GO:0004510	tryptophan 5-monooxygenase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0035187 MGI:MGI:2651811 MGI:MGI:98796 PANTHER:PTN000158467 RGD:3895	F		Seeded From UniProt	complete
enables	GO:0004497	monooxygenase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001273 InterPro:IPR018301 InterPro:IPR036951	F		Seeded From UniProt	complete
enables	GO:0004510	tryptophan 5-monooxygenase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005963	F		Seeded From UniProt	complete
enables	GO:0005506	iron ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001273 InterPro:IPR018301 InterPro:IPR036951	F		Seeded From UniProt	complete
involved_in	GO:0009072	aromatic amino acid family metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001273 InterPro:IPR018301 InterPro:IPR036951	P		Seeded From UniProt	complete
enables	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR019773 InterPro:IPR019774	F		Seeded From UniProt	complete
involved_in	GO:0042427	serotonin biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005963	P		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001273 InterPro:IPR005963 InterPro:IPR018301 InterPro:IPR019773 InterPro:IPR019774 InterPro:IPR036951	P		Seeded From UniProt	complete
enables	GO:0004510	tryptophan 5-monooxygenase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:1.14.16.4	F		Seeded From UniProt	complete
enables	GO:0004497	monooxygenase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0503	F		Seeded From UniProt	complete
involved_in	GO:0042427	serotonin biosynthetic process	GO_REF:0000037 GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0724 UniPathway:UPA00846	P		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
enables	GO:0016491	oxidoreductase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	F		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	P		Seeded From UniProt	complete
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References

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