CHICK:TIMP2

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	TIMP2
Protein Name(s)	Metalloproteinase inhibitor 2 Tissue inhibitor of metalloproteinases 2 TIMP-2
External Links
UniProt	O42146
EMBL	AF004664
RefSeq	NP_989629.1
UniGene	Gga.2965
ProteinModelPortal	O42146
SMR	O42146
MEROPS	I35.002
GeneID	374178
KEGG	gga:374178
CTD	7077
HOVERGEN	HBG068749
InParanoid	O42146
PhylomeDB	O42146
NextBio	20813684
PRO	PR:O42146
Proteomes	UP000000539
GO	GO:0005576 GO:0046872 GO:0008191
Gene3D	3.90.370.10
InterPro	IPR001134 IPR001820 IPR008993 IPR015613 IPR027465
PANTHER	PTHR11844 PTHR11844:SF7
Pfam	PF00965
SMART	SM00206
SUPFAM	SSF50242
PROSITE	PS50189 PS00288

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0051045	negative regulation of membrane protein ectodomain proteolysis		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000931945 UniProtKB:P01033 UniProtKB:P35625	P		Seeded From UniProt	complete
involved_in	GO:0034097	response to cytokine		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000931946 RGD:61312 RGD:621675 RGD:69077	P		Seeded From UniProt	complete
part_of	GO:0031012	extracellular matrix		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98752 PANTHER:PTN000931945	C		Seeded From UniProt	complete
involved_in	GO:0010951	negative regulation of endopeptidase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000931945 UniProtKB:P01033	P		Seeded From UniProt	complete
involved_in	GO:0010033	response to organic substance		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000931945 RGD:3865 RGD:621675	P		Seeded From UniProt	complete
involved_in	GO:0009725	response to hormone		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000931946 RGD:3865 RGD:69077	P		Seeded From UniProt	complete
enables	GO:0008191	metalloendopeptidase inhibitor activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0025879 MGI:MGI:98753 PANTHER:PTN000931945 RGD:61312 UniProtKB:P01033	F		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000931945 RGD:61312 RGD:69077 UniProtKB:P01033 ZFIN:ZDB-GENE-030612-1	C		Seeded From UniProt	complete
enables	GO:0002020	protease binding		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000931945 RGD:621675 UniProtKB:P16035	F		Seeded From UniProt	complete
enables	GO:0008191	metalloendopeptidase inhibitor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001820 InterPro:IPR015613	F		Seeded From UniProt	complete
involved_in	GO:0010951	negative regulation of endopeptidase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR015613	P		Seeded From UniProt	complete
enables	GO:0004857	enzyme inhibitor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0481	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
enables	GO:0030414	peptidase inhibitor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0646	F		Seeded From UniProt	complete
involved_in	GO:0010466	negative regulation of peptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0646	P		Seeded From UniProt	complete
enables	GO:0008191	metalloendopeptidase inhibitor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0483	F		Seeded From UniProt	complete
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References

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