CHICK:SEM3A

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	SEMA3A (synonyms: COLL1)
Protein Name(s)	Semaphorin-3A Collapsin-1 COLL-1
External Links
UniProt	Q90607
EMBL	U02528
PIR	A49069
RefSeq	NP_990308.2
UniGene	Gga.487
ProteinModelPortal	Q90607
SMR	Q90607
STRING	9031.ENSGALP00000010577
PaxDb	Q90607
GeneID	395825
KEGG	gga:395825
CTD	10371
eggNOG	NOG305380
HOGENOM	HOG000039964
HOVERGEN	HBG055071
InParanoid	Q90607
KO	K06840
PhylomeDB	Q90607
NextBio	20815893
PRO	PR:Q90607
Proteomes	UP000000539
GO	GO:0005576 GO:0016020 GO:0004872 GO:0030154 GO:0007399
Gene3D	2.130.10.10 2.60.40.10
InterPro	IPR007110 IPR013783 IPR003599 IPR013151 IPR016201 IPR002165 IPR001627 IPR027231 IPR015943
PANTHER	PTHR11036
Pfam	PF00047 PF01437 PF01403
SMART	SM00409 SM00423 SM00630
SUPFAM	SSF101912 SSF103575
PROSITE	PS50835 PS51004

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
part_of	GO:0005615	extracellular space	PMID:9331347^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0038191	neuropilin binding	PMID:9331347^[1]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:F1N8P1	F		Seeded From UniProt	complete
enables	GO:0038191	neuropilin binding	PMID:9331347^[1]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P79795	F		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:18039974^[2]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:2000009	negative regulation of protein localization to cell surface	PMID:18039974^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(GO:0044295) transports_or_maintains_localization_of:(UniProtKB:P79795)\|occurs_in(GO:0044295) transports_or_maintains_localization_of:(UniProtKB:F1N8P1)	Seeded From UniProt	complete
involved_in	GO:1990535	neuron projection maintenance	PMID:18039974^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(GO:0044295)	Seeded From UniProt	complete
part_of	GO:0044297	cell body	PMID:18039974^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000100) part_of:(UBERON:0001780)	Seeded From UniProt	complete
involved_in	GO:0008045	motor neuron axon guidance	PMID:18039974^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(UBERON:0006839) occurs_in:(UBERON:0002240)	Seeded From UniProt	complete
involved_in	GO:0097156	fasciculation of motor neuron axon	PMID:18039974^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(UBERON:0006838) occurs_in:(UBERON:0002240)	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	PMID:16540575^[3]	ECO:0006063	over expression analysis evidence used in manual assertion		C	part_of:(UBERON:0000956)	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	PMID:16540575^[3]	ECO:0005589	confocal microscopy evidence used in manual assertion		C	part_of:(UBERON:0000956)	Seeded From UniProt	complete
involved_in	GO:0050807	regulation of synapse organization	PMID:16540575^[3]	ECO:0006063	over expression analysis evidence used in manual assertion		P	occurs_in:(GO:0098978) occurs_in:(UBERON:0000956)	Seeded From UniProt	complete
involved_in	GO:0050807	regulation of synapse organization	PMID:16540575^[3]	ECO:0005589	confocal microscopy evidence used in manual assertion		P	occurs_in:(GO:0098978) occurs_in:(UBERON:0000956)	Seeded From UniProt	complete
involved_in	GO:2001224	positive regulation of neuron migration	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107558 PANTHER:PTN000112586	P		Seeded From UniProt	complete
involved_in	GO:0071526	semaphorin-plexin signaling pathway	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107556 MGI:MGI:107557 MGI:MGI:107558 MGI:MGI:107560 MGI:MGI:109252 MGI:MGI:1203727 MGI:MGI:1340034 PANTHER:PTN000867340 UniProtKB:Q92854	P		Seeded From UniProt	complete
involved_in	GO:0050919	negative chemotaxis	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107558 MGI:MGI:1096347 PANTHER:PTN000744245	P		Seeded From UniProt	complete
involved_in	GO:0048843	negative regulation of axon extension involved in axon guidance	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107558 MGI:MGI:1096347 PANTHER:PTN000867340 RGD:1308650	P		Seeded From UniProt	complete
enables	GO:0045499	chemorepellent activity	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107558 MGI:MGI:1096347 PANTHER:PTN000867340 UniProtKB:Q13275	F		Seeded From UniProt	complete
enables	GO:0038191	neuropilin binding	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107558 PANTHER:PTN000867406 UniProtKB:A0A1D5PZ68 UniProtKB:O42236 UniProtKB:O42237 UniProtKB:Q90607 UniProtKB:Q90663	F		Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000112586 RGD:3657	C		Seeded From UniProt	complete
involved_in	GO:0030335	positive regulation of cell migration	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:109244 PANTHER:PTN000867340 UniProtKB:Q92854	P		Seeded From UniProt	complete
enables	GO:0030215	semaphorin receptor binding	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107556 MGI:MGI:107557 MGI:MGI:107558 MGI:MGI:109244 MGI:MGI:1202889 MGI:MGI:1203727 MGI:MGI:1338032 MGI:MGI:1340034 MGI:MGI:2387661 PANTHER:PTN000867340 UniProtKB:Q92854 WB:WBGene00003111 WB:WBGene00004889	F		Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1203727 PANTHER:PTN000112372 UniProtKB:Q92854	C		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107557 MGI:MGI:109244 PANTHER:PTN000744245 UniProtKB:A0A1D5PZ68 UniProtKB:O42236 UniProtKB:O42237 UniProtKB:Q90607 UniProtKB:Q90663	C		Seeded From UniProt	complete
involved_in	GO:0001755	neural crest cell migration	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107557 MGI:MGI:1096347 PANTHER:PTN000867340 ZFIN:ZDB-GENE-050513-4	P		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	Reactome:R-NUL-421138 Reactome:R-NUL-421136	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
involved_in	GO:0007399	nervous system development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0524	P		Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P		Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0221	P		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 Feiner, L et al. (1997) Secreted chick semaphorins bind recombinant neuropilin with similar affinities but bind different subsets of neurons in situ. Neuron 19 539-45 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 Moret, F et al. (2007) Semaphorin and neuropilin co-expression in motoneurons sets axon sensitivity to environmental semaphorin sources during motor axon pathfinding. Development 134 4491-501 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 Morita, A et al. (2006) Regulation of dendritic branching and spine maturation by semaphorin3A-Fyn signaling. J. Neurosci. 26 2971-80 PubMed GONUTS page
↑ ^4.00 ^4.01 ^4.02 ^4.03 ^4.04 ^4.05 ^4.06 ^4.07 ^4.08 ^4.09 ^4.10 ^4.11 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:9331347-1] 1.0 ^1.1 ^1.2 Feiner, L et al. (1997) Secreted chick semaphorins bind recombinant neuropilin with similar affinities but bind different subsets of neurons in situ. Neuron 19 539-45 PubMed GONUTS page

[PMID:18039974-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 Moret, F et al. (2007) Semaphorin and neuropilin co-expression in motoneurons sets axon sensitivity to environmental semaphorin sources during motor axon pathfinding. Development 134 4491-501 PubMed GONUTS page

[PMID:16540575-3] 3.0 ^3.1 ^3.2 ^3.3 Morita, A et al. (2006) Regulation of dendritic branching and spine maturation by semaphorin3A-Fyn signaling. J. Neurosci. 26 2971-80 PubMed GONUTS page

[PMID:21873635-4] 4.00 ^4.01 ^4.02 ^4.03 ^4.04 ^4.05 ^4.06 ^4.07 ^4.08 ^4.09 ^4.10 ^4.11 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:SEM3A

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