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CHICK:Q9PU44
Contents
| Species (Taxon ID) | Gallus gallus (Chicken). (9031) | |
| Gene Name(s) | cyp3A37 (ECO:0000313 with EMBL:CAB62060.1) | |
| Protein Name(s) | Cytochrome P450 (ECO:0000313 with EMBL:CAB62060.1) | |
| External Links | ||
| UniProt | Q9PU44 | |
| EMBL | AJ250337 | |
| RefSeq | NP_001001751.1 | |
| UniGene | Gga.1163 | |
| ProteinModelPortal | Q9PU44 | |
| SMR | Q9PU44 | |
| GeneID | 414832 | |
| KEGG | gga:414832 | |
| CTD | 1551 | |
| HOGENOM | HOG000039127 | |
| HOVERGEN | HBG108567 | |
| KO | K07424 | |
| PhylomeDB | Q9PU44 | |
| NextBio | 20818730 | |
| GO | GO:0020037 GO:0005506 GO:0016712 | |
| Gene3D | 1.10.630.10 | |
| InterPro | IPR001128 IPR017972 IPR008072 IPR002402 | |
| Pfam | PF00067 | |
| PRINTS | PR00464 PR01689 PR00385 | |
| SUPFAM | SSF48264 | |
| PROSITE | PS00086 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0045177 |
apical part of cell |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016020 |
membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016324 |
apical plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042445 |
hormone metabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
has_direct_input:(CHEBI:17347)|has_direct_input:(CHEBI:16422) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0008202 |
steroid metabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
has_direct_input:(CHEBI:17347)|has_direct_input:(CHEBI:16422) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:1901615 |
organic hydroxy compound metabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
has_direct_input:(CHEBI:17347)|has_direct_input:(CHEBI:16422) |
Seeded From UniProt |
complete | ||
|
enables |
GO:0050649 |
testosterone 6-beta-hydroxylase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008395 |
steroid hydroxylase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
|
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042448 |
progesterone metabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005623 |
cell |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0002107) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0017144 |
drug metabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046677 |
response to antibiotic |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0043385 |
mycotoxin metabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
has_direct_input:(CHEBI:9381) |
Seeded From UniProt |
complete | ||
|
enables |
GO:0032451 |
demethylase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0070988 |
demethylation |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0032451 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004497 |
monooxygenase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005506 |
iron ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001128 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0020037 |
heme binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001128 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001128 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016020 |
membrane |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004497 |
monooxygenase activity |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Guo, M et al. (2014) E. coli infection modulates the pharmacokinetics of oral enrofloxacin by targeting P-glycoprotein in small intestine and CYP450 3A in liver and kidney of broilers. PLoS ONE 9 e87781 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Ourlin, JC et al. (2000) Cloning and functional expression of a first inducible avian cytochrome P450 of the CYP3A subfamily (CYP3A37). Arch. Biochem. Biophys. 373 375-84 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Zhang, LL et al. (2011) Effects of fluoroquinolones on CYP4501A and 3A in male broilers. Res. Vet. Sci. 90 99-105 PubMed GONUTS page
- ↑ 4.0 4.1 Yuan, Y et al. (2013) T-2 toxin is hydroxylated by chicken CYP3A37. Food Chem. Toxicol. 62 622-7 PubMed GONUTS page
d
m
o
- GO:0005623 ! obsolete cell
- GO:1901615 ! obsolete organic hydroxy compound metabolic process
- GO:0055114 ! obsolete oxidation-reduction process
- GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
- GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
- GO:0016491 ! oxidoreductase activity
