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CHICK:Q9DEG0

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) Cremp (ECO:0000313 with EMBL:BAB16878.1)
Protein Name(s) Complement regulatory membrane protein (ECO:0000313 with EMBL:BAB16878.1)
External Links
UniProt Q9DEG0
EMBL AB035592
RefSeq NP_989995.1
UniGene Gga.3349
ProteinModelPortal Q9DEG0
STRING 9031.ENSGALP00000001779
PaxDb Q9DEG0
PRIDE Q9DEG0
GeneID 395384
KEGG gga:395384
CTD 722
eggNOG NOG12793
HOGENOM HOG000202920
PhylomeDB Q9DEG0
Reactome REACT_172668
REACT_172673
NextBio 20815468
GO GO:0005886
GO:0006956
GO:0045087
GO:0030449
InterPro IPR000436
Pfam PF00084
SMART SM00032
SUPFAM SSF57535
PROSITE PS50923

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0005886

plasma membrane

PMID:11123320[1]

ECO:0000314

C

Figure 4 shows Cremp localizing to the surface of the transfected CHO cell via flow cytometry and anti-Cremp antibody staining.

complete
CACAO 10926

GO:0045916

negative regulation of complement activation

PMID:11123320[1]

ECO:0000314

P

Figure 6 panels A and B show that CHO cells expressing Cremp are protected from cytotoxicity by C in chicken serum.

complete
CACAO 10927

involved_in

GO:0045918

negative regulation of cytolysis

PMID:11123320[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

PMID:11123320[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:11123320[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

involved_in

GO:0030449

regulation of complement activation

Reactome:R-GGA-2132281

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

Reactome:R-GGA-2530584

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Inoue, N et al. (2001) A novel chicken membrane-associated complement regulatory protein: molecular cloning and functional characterization. J. Immunol. 166 424-31 PubMed GONUTS page