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CHICK:Q9BD54

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) CD74 (ECO:0000313 with EMBL:CAC27415.3)
Protein Name(s) MHC class II-associated invariant chain (ECO:0000313 with EMBL:CAC27415.3)
External Links
UniProt Q9BD54
EMBL AJ292038
UniGene Gga.4414
ProteinModelPortal Q9BD54
MEROPS I31.002
PRIDE Q9BD54
HOGENOM HOG000013145
HOVERGEN HBG004444
GO GO:0016020
GO:0019882
GO:0006955
GO:0006886
Gene3D 1.10.870.10
4.10.800.10
InterPro IPR015386
IPR022339
IPR011988
IPR000716
PANTHER PTHR14093
Pfam PF09307
PF08831
PF00086
PIRSF PIRSF001992
PRINTS PR01990
SMART SM00211
SUPFAM SSF48305
SSF57610
PROSITE PS51162

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005737

cytoplasm

PMID:24948007[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0042611

MHC protein complex

PMID:24948007[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0042288

MHC class I protein binding

PMID:24948007[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:U3PTD3

F

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

PMID:23370168[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:23370168[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0035718

macrophage migration inhibitory factor binding

PMID:25086294[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

PMID:25086294[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

PMID:25086294[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0006886

intracellular protein transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015386

P

Seeded From UniProt

complete

involved_in

GO:0006955

immune response

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015386

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015386

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011988
InterPro:IPR022339
InterPro:IPR036613

C

Seeded From UniProt

complete

involved_in

GO:0019882

antigen processing and presentation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011988
InterPro:IPR015386
InterPro:IPR022339

P

Seeded From UniProt

complete

enables

GO:0042289

MHC class II protein binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011988
InterPro:IPR015386
InterPro:IPR022339
InterPro:IPR036613

F

Seeded From UniProt

complete

involved_in

GO:0070206

protein trimerization

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR036613

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Chen, F et al. (2014) Allele-dependent association of chicken MHC class I molecules with the invariant chain. Vet. Immunol. Immunopathol. 160 273-80 PubMed GONUTS page
  2. 2.0 2.1 Chen, F et al. (2013) Cross-species association of quail invariant chain with chicken and mouse MHC II molecules. Dev. Comp. Immunol. 40 20-7 PubMed GONUTS page
  3. 3.0 3.1 3.2 Kim, S et al. (2014) Both host and parasite MIF molecules bind to chicken macrophages via CD74 surface receptor. Dev. Comp. Immunol. 47 319-26 PubMed GONUTS page