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CHICK:Q90Z44

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) No Information Provided.
Protein Name(s) Slit2 protein (ECO:0000313 with EMBL:AAK94291.1)
External Links
UniProt Q90Z44
EMBL AF364045
UniGene Gga.39631
ProteinModelPortal Q90Z44
HOGENOM HOG000116120
HOVERGEN HBG057959
PhylomeDB Q90Z44
GO GO:0005509
GO:0007411
GO:0048839
GO:0060173
GO:0051451
Gene3D 2.60.120.200
InterPro IPR013320
IPR000483
IPR006207
IPR000742
IPR001881
IPR013032
IPR000152
IPR018097
IPR003645
IPR001791
IPR001611
IPR003591
IPR000372
Pfam PF00008
PF00054
PF00560
PF13855
PF01463
PF01462
SMART SM00041
SM00181
SM00179
SM00274
SM00282
SM00369
SM00082
SM00013
SUPFAM SSF49899
PROSITE PS00010
PS01185
PS01225
PS00022
PS01186
PS50026
PS01187
PS50025
PS51450

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0090288

negative regulation of cellular response to growth factor stimulus

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0090260

negative regulation of retinal ganglion cell axon guidance

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0090024

negative regulation of neutrophil chemotaxis

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0071676

negative regulation of mononuclear cell migration

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0071672

negative regulation of smooth muscle cell chemotaxis

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0071504

cellular response to heparin

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0070100

negative regulation of chemokine-mediated signaling pathway

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

part_of

GO:0070062

extracellular exosome

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

C

Seeded From UniProt

complete

involved_in

GO:0061364

apoptotic process involved in luteolysis

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0051414

response to cortisol

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0051058

negative regulation of small GTPase mediated signal transduction

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0050929

induction of negative chemotaxis

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0050919

negative chemotaxis

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0048846

axon extension involved in axon guidance

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0048754

branching morphogenesis of an epithelial tube

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

enables

GO:0048495

Roundabout binding

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

F

Seeded From UniProt

complete

enables

GO:0043394

proteoglycan binding

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

F

Seeded From UniProt

complete

enables

GO:0043237

laminin-1 binding

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

F

Seeded From UniProt

complete

involved_in

GO:0043116

negative regulation of vascular permeability

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0043086

negative regulation of catalytic activity

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0043065

positive regulation of apoptotic process

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

enables

GO:0042803

protein homodimerization activity

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

F

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

F

Seeded From UniProt

complete

involved_in

GO:0035385

Roundabout signaling pathway

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0034260

negative regulation of GTPase activity

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0032870

cellular response to hormone stimulus

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0031290

retinal ganglion cell axon guidance

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0030837

negative regulation of actin filament polymerization

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0030336

negative regulation of cell migration

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0030308

negative regulation of cell growth

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0021972

corticospinal neuron axon guidance through spinal cord

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0021836

chemorepulsion involved in postnatal olfactory bulb interneuron migration

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

NOT|involved_in

GO:0021834

chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0014912

negative regulation of smooth muscle cell migration

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0010596

negative regulation of endothelial cell migration

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0010593

negative regulation of lamellipodium assembly

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

enables

GO:0008201

heparin binding

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

F

Seeded From UniProt

complete

involved_in

GO:0008045

motor neuron axon guidance

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0007411

axon guidance

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

C

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

C

Seeded From UniProt

complete

enables

GO:0005095

GTPase inhibitor activity

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

F

Seeded From UniProt

complete

involved_in

GO:0002689

negative regulation of leukocyte chemotaxis

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0002042

cell migration involved in sprouting angiogenesis

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0001933

negative regulation of protein phosphorylation

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

involved_in

GO:0001657

ureteric bud development

PMID:11472852[1]

ECO:0000247

sequence alignment evidence used in manual assertion

UniProtKB:O94813

P

Seeded From UniProt

complete

part_of

GO:0005623

cell

PMID:26188027[2]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(CL:0000023)
  • part_of:(UBERON:0001305)|part_of:(CL:0000501)
  • part_of:(UBERON:0001305)

Seeded From UniProt

complete

involved_in

GO:0060173

limb development

PMID:11472852[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0051451

myoblast migration

PMID:11472852[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0048839

inner ear development

PMID:18213576[3]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007411

axon guidance

PMID:11472852[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001881
InterPro:IPR018097

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 1.18 1.19 1.20 1.21 1.22 1.23 1.24 1.25 1.26 1.27 1.28 1.29 1.30 1.31 1.32 1.33 1.34 1.35 1.36 1.37 1.38 1.39 1.40 1.41 1.42 1.43 1.44 1.45 1.46 1.47 1.48 Vargesson, N et al. (2001) Expression patterns of Slit and Robo family members during vertebrate limb development. Mech. Dev. 106 175-80 PubMed GONUTS page
  2. Qin, N et al. (2015) New insights into implication of the SLIT/ROBO pathway in the prehierarchical follicle development of hen ovary. Poult. Sci. 94 2235-46 PubMed GONUTS page
  3. Battisti, AC & Fekete, DM (2008) Slits and Robos in the developing chicken inner ear. Dev. Dyn. 237 476-84 PubMed GONUTS page