CHICK:Q90WK2

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	PDGF-A (L) (ECO:0000313 with EMBL:BAB62541.1)
Protein Name(s)	Platelet-derived growth factor A chain long form (ECO:0000313 with EMBL:BAB62541.1)
External Links
UniProt	Q90WK2
EMBL	AB031022
UniGene	Gga.3899
ProteinModelPortal	Q90WK2
HOGENOM	HOG000286027
HOVERGEN	HBG053546
PhylomeDB	Q90WK2
PRO	PR:Q90WK2
GO	GO:0016020 GO:0051781
Gene3D	2.10.90.10
InterPro	IPR029034 IPR023581 IPR000072 IPR006782
Pfam	PF00341 PF04692
SMART	SM00141
SUPFAM	SSF57501
PROSITE	PS00249 PS50278

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0070374	positive regulation of ERK1 and ERK2 cascade	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000180420 UniProtKB:P01127 UniProtKB:P04085	P	Seeded From UniProt	complete
involved_in	GO:0048008	platelet-derived growth factor receptor signaling pathway	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1859631 PANTHER:PTN000180420 RGD:3283 UniProtKB:P01127 UniProtKB:P04085 UniProtKB:Q9NRA1	P	Seeded From UniProt	complete
involved_in	GO:0043406	positive regulation of MAP kinase activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000180420 RGD:3283 UniProtKB:P01127 UniProtKB:P04085	P	Seeded From UniProt	complete
involved_in	GO:0031954	positive regulation of protein autophosphorylation	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000908679 UniProtKB:P01127 UniProtKB:P04085	P	Seeded From UniProt	complete
involved_in	GO:0030335	positive regulation of cell migration	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97528 PANTHER:PTN000180420 UniProtKB:B1H0W5 UniProtKB:P01127 UniProtKB:P04085	P	Seeded From UniProt	complete
involved_in	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97528 PANTHER:PTN000180420 UniProtKB:P01127 UniProtKB:P04085	P	Seeded From UniProt	complete
involved_in	GO:0008284	positive regulation of cell population proliferation	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1859631 MGI:MGI:97527 PANTHER:PTN000908679 RGD:3282 UniProtKB:P01127 UniProtKB:P04085 UniProtKB:Q9NRA1	P	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97527 PANTHER:PTN000908679 RGD:3283 RGD:621880 UniProtKB:P04085 UniProtKB:Q9NRA1	C	Seeded From UniProt	complete
enables	GO:0005161	platelet-derived growth factor receptor binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1859631 PANTHER:PTN000180420 UniProtKB:P01127 UniProtKB:P04085 UniProtKB:Q9NRA1	F	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0008083	P	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0008083	P	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0008083	P	Seeded From UniProt	complete
involved_in	GO:0070374	positive regulation of ERK1 and ERK2 cascade	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	P	Seeded From UniProt	complete
involved_in	GO:0051897	positive regulation of protein kinase B signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	P	Seeded From UniProt	complete
involved_in	GO:0050919	negative chemotaxis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	P	Seeded From UniProt	complete
enables	GO:0048407	platelet-derived growth factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	F	Seeded From UniProt	complete
involved_in	GO:0048146	positive regulation of fibroblast proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	P	Seeded From UniProt	complete
involved_in	GO:0048008	platelet-derived growth factor receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	P	Seeded From UniProt	complete
enables	GO:0046982	protein heterodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	F	Seeded From UniProt	complete
involved_in	GO:0043410	positive regulation of MAPK cascade	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	P	Seeded From UniProt	complete
involved_in	GO:0043406	positive regulation of MAP kinase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	P	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	F	Seeded From UniProt	complete
involved_in	GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	P	Seeded From UniProt	complete
involved_in	GO:0031954	positive regulation of protein autophosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	P	Seeded From UniProt	complete
involved_in	GO:0030335	positive regulation of cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	P	Seeded From UniProt	complete
involved_in	GO:0014910	regulation of smooth muscle cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	P	Seeded From UniProt	complete
involved_in	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	P	Seeded From UniProt	complete
involved_in	GO:0010544	negative regulation of platelet activation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	P	Seeded From UniProt	complete
involved_in	GO:0010512	negative regulation of phosphatidylinositol biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	P	Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	C	Seeded From UniProt	complete
involved_in	GO:0009611	response to wounding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	P	Seeded From UniProt	complete
involved_in	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	P	Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	F	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	C	Seeded From UniProt	complete
enables	GO:0005518	collagen binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	F	Seeded From UniProt	complete
enables	GO:0005161	platelet-derived growth factor receptor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P04085 ensembl:ENSP00000346508	F	Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000072 InterPro:IPR006782	F	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000072 InterPro:IPR006782	C	Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0339	F	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:Q90WK2

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Annotations

Notes

References

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