CHICK:Q8AYD0

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	No Information Provided.
Protein Name(s)	Vascular endothelial cadherin
External Links
UniProt	Q8AYD0
EMBL	AF522067
RefSeq	NP_989558.1
UniGene	Gga.5171
PDB	3PPE
PDBsum	3PPE
ProteinModelPortal	Q8AYD0
STRING	9031.ENSGALP00000008445
PRIDE	Q8AYD0
GeneID	374068
KEGG	gga:374068
CTD	1003
eggNOG	NOG270902
HOGENOM	HOG000231252
HOVERGEN	HBG005217
InParanoid	Q8AYD0
KO	K06533
NextBio	20813589
PRO	PR:Q8AYD0
GO	GO:0016021 GO:0005886 GO:0005509 GO:0060317 GO:0007156
Gene3D	2.60.40.60 4.10.900.10
InterPro	IPR002126 IPR015919 IPR020894 IPR000233 IPR027397
Pfam	PF00028 PF01049
PRINTS	PR00205
SMART	SM00112
SUPFAM	SSF49313
PROSITE	PS00232 PS50268

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0060317	cardiac epithelial to mesenchymal transition	PMID:17250821^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:2000114	regulation of establishment of cell polarity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:105057 PANTHER:PTN000616731 UniProtKB:P33151	P	Seeded From UniProt	complete
involved_in	GO:0098609	cell-cell adhesion	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:105057 MGI:MGI:88354 MGI:MGI:88356 PANTHER:PTN000616280 RGD:69280 UniProtKB:O93319 UniProtKB:P12830 UniProtKB:Q86UP0	P	Seeded From UniProt	complete
enables	GO:0045296	cadherin binding	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000616280 UniProtKB:P10288 UniProtKB:P55290	F	Seeded From UniProt	complete
involved_in	GO:0044331	cell-cell adhesion mediated by cadherin	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88355 PANTHER:PTN000616280 UniProtKB:P10288	P	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:99551 PANTHER:PTN000616280	F	Seeded From UniProt	complete
involved_in	GO:0034332	adherens junction organization	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000616280 UniProtKB:P12830 ZFIN:ZDB-GENE-990415-171	P	Seeded From UniProt	complete
part_of	GO:0016342	catenin complex	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88354 PANTHER:PTN000616280 UniProtKB:P12830 UniProtKB:P19022 ZFIN:ZDB-GENE-990415-171	C	Seeded From UniProt	complete
involved_in	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1095414 MGI:MGI:88354 MGI:MGI:88355 PANTHER:PTN000616280 RGD:2321 RGD:69280 UniProtKB:P55290	P	Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1095414 MGI:MGI:88354 MGI:MGI:88355 PANTHER:PTN000616280 UniProtKB:P10288 UniProtKB:P33150 UniProtKB:P33151	C	Seeded From UniProt	complete
enables	GO:0008092	cytoskeletal protein binding	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88354 PANTHER:PTN000616280	F	Seeded From UniProt	complete
involved_in	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1095414 MGI:MGI:88355 MGI:MGI:99218 PANTHER:PTN000616280 UniProtKB:P55290	P	Seeded From UniProt	complete
involved_in	GO:0007043	cell-cell junction assembly	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000616280 UniProtKB:P33151	P	Seeded From UniProt	complete
part_of	GO:0005923	bicellular tight junction	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:105057 PANTHER:PTN000616731	C	Seeded From UniProt	complete
part_of	GO:0005913	cell-cell adherens junction	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:105057 MGI:MGI:88354 MGI:MGI:88356 PANTHER:PTN000616280 RGD:69280 UniProtKB:P10288 UniProtKB:P12830 UniProtKB:P19022 UniProtKB:P33151	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:105057 MGI:MGI:107435 MGI:MGI:1095414 MGI:MGI:88354 MGI:MGI:88355 MGI:MGI:88356 MGI:MGI:99217 MGI:MGI:99551 PANTHER:PTN000616280 RGD:619745 RGD:621089 RGD:69279 RGD:69280 UniProtKB:O93319 UniProtKB:P10288 UniProtKB:P12830 UniProtKB:P19022 UniProtKB:P22223 UniProtKB:P33151 UniProtKB:P55283 UniProtKB:P55290 UniProtKB:Q6ZTQ4 UniProtKB:Q90763 ZFIN:ZDB-GENE-010606-1	C	Seeded From UniProt	complete
enables	GO:0005509	calcium ion binding	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88354 PANTHER:PTN000616280 UniProtKB:Q86UP0	F	Seeded From UniProt	complete
involved_in	GO:0000902	cell morphogenesis	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000616280 ZFIN:ZDB-GENE-990415-171	P	Seeded From UniProt	complete
involved_in	GO:2000114	regulation of establishment of cell polarity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55284 ensembl:ENSMUSP00000034339	P	Seeded From UniProt	complete
involved_in	GO:0098609	cell-cell adhesion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55284 ensembl:ENSMUSP00000034339	P	Seeded From UniProt	complete
part_of	GO:0071944	cell periphery	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55284 ensembl:ENSMUSP00000034339	C	Seeded From UniProt	complete
part_of	GO:0030054	cell junction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55284 ensembl:ENSMUSP00000034339	C	Seeded From UniProt	complete
enables	GO:0019903	protein phosphatase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55284 ensembl:ENSMUSP00000034339	F	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55284 ensembl:ENSMUSP00000034339	C	Seeded From UniProt	complete
involved_in	GO:0008285	negative regulation of cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55284 ensembl:ENSMUSP00000034339	P	Seeded From UniProt	complete
part_of	GO:0005923	bicellular tight junction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55284 ensembl:ENSMUSP00000034339	C	Seeded From UniProt	complete
part_of	GO:0005913	cell-cell adherens junction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55284 ensembl:ENSMUSP00000034339	C	Seeded From UniProt	complete
part_of	GO:0005912	adherens junction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55284 ensembl:ENSMUSP00000034339	C	Seeded From UniProt	complete
part_of	GO:0005911	cell-cell junction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55284 ensembl:ENSMUSP00000034339	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55284 ensembl:ENSMUSP00000034339	C	Seeded From UniProt	complete
involved_in	GO:0001955	blood vessel maturation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55284 ensembl:ENSMUSP00000034339	P	Seeded From UniProt	complete
involved_in	GO:0001955	blood vessel maturation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR030052	P	Seeded From UniProt	complete
enables	GO:0005509	calcium ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000233 InterPro:IPR002126 InterPro:IPR015919 InterPro:IPR030052	F	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR020894	C	Seeded From UniProt	complete
involved_in	GO:0007155	cell adhesion	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR020894 InterPro:IPR030052	P	Seeded From UniProt	complete
involved_in	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000233 InterPro:IPR002126	P	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002126 InterPro:IPR015919	C	Seeded From UniProt	complete
involved_in	GO:0098609	cell-cell adhesion	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR039808	P	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
part_of	GO:0030054	cell junction	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0965 UniProtKB-SubCell:SL-0038	C	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F	Seeded From UniProt	complete
involved_in	GO:0007155	cell adhesion	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0130	P	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Mercado-Pimentel, ME et al. (2007) Endoglin and Alk5 regulate epithelial-mesenchymal transformation during cardiac valve formation. Dev. Biol. 304 420-32 PubMed GONUTS page
↑ ^2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 ^2.11 ^2.12 ^2.13 ^2.14 ^2.15 ^2.16 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:17250821-1] Mercado-Pimentel, ME et al. (2007) Endoglin and Alk5 regulate epithelial-mesenchymal transformation during cardiac valve formation. Dev. Biol. 304 420-32 PubMed GONUTS page

[PMID:21873635-2] 2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 ^2.11 ^2.12 ^2.13 ^2.14 ^2.15 ^2.16 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:Q8AYD0

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Annotations

Notes

References

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