CHICK:Q703P0

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	No Information Provided.
Protein Name(s)	Corticotropin releasing hormone (ECO:0000313 with EMBL:CAF18561.2) Uncharacterized protein (ECO:0000313 with Ensembl:ENSGALP00000024980)
External Links
UniProt	Q703P0
EMBL	AADN03001912 AJ621492
RefSeq	NP_001116503.1
UniGene	Gga.11323
SMR	Q703P0
STRING	9031.ENSGALP00000024980
Ensembl	ENSGALT00000025026
GeneID	404297
KEGG	gga:404297
CTD	1392
eggNOG	NOG38852
GeneTree	ENSGT00510000048573
HOGENOM	HOG000004762
HOVERGEN	HBG001951
KO	K05256
OMA	SALGGHQ
OrthoDB	EOG7NSB43
PhylomeDB	Q703P0
TreeFam	TF332956
Reactome	REACT_245585 REACT_246971
NextBio	20817642
PRO	PR:Q703P0
Proteomes	UP000000539
GO	GO:0005615 GO:0030325 GO:0006704 GO:0006954 GO:0035641 GO:0030324 GO:0051464 GO:2000310 GO:0001963
InterPro	IPR018446 IPR000187 IPR003620
PANTHER	PTHR15035
Pfam	PF00473
PRINTS	PR01612
SMART	SM00039
PROSITE	PS00511

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:2000852	regulation of corticosterone secretion	PMID:17936761^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:2000854	positive regulation of corticosterone secretion	PMID:15082159^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:2000294	positive regulation of defecation	PMID:15082159^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0071625	vocalization behavior	PMID:15082159^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
NOT\|involved_in	GO:2000983	regulation of ATP citrate synthase activity	PMID:18786646^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
NOT\|involved_in	GO:0051341	regulation of oxidoreductase activity	PMID:18786646^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0004601	peroxidase activity	PMID:18786646^[3]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
NOT\|enables	GO:0004601	peroxidase activity	PMID:18786646^[3]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:2000985	positive regulation of ATP citrate synthase activity	PMID:18620026^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
NOT\|involved_in	GO:2000983	regulation of ATP citrate synthase activity	PMID:18620026^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0051353	positive regulation of oxidoreductase activity	PMID:18620026^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
NOT\|involved_in	GO:0051341	regulation of oxidoreductase activity	PMID:18620026^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0001659	temperature homeostasis	PMID:18620026^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:6340106^[5]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001264) part_of:(UBERON:0000006)	Seeded From UniProt	complete
enables	GO:0017045	corticotropin-releasing hormone activity	PMID:19393716^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0032099	negative regulation of appetite	PMID:19393716^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0070093	negative regulation of glucagon secretion	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001030516 RGD:620505	P		Seeded From UniProt	complete
involved_in	GO:0051464	positive regulation of cortisol secretion	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001030516 UniProtKB:P06850	P		Seeded From UniProt	complete
involved_in	GO:0032811	negative regulation of epinephrine secretion	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001030516 RGD:620505	P		Seeded From UniProt	complete
enables	GO:0017045	corticotropin-releasing hormone activity	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001030516 UniProtKB:Q703P0	F		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001030516 RGD:620505 UniProtKB:P06850	C		Seeded From UniProt	complete
involved_in	GO:0098869	cellular oxidant detoxification	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004601	P		Seeded From UniProt	complete
involved_in	GO:0098869	cellular oxidant detoxification	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004601	P		Seeded From UniProt	complete
involved_in	GO:2000310	regulation of NMDA receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06850 ensembl:ENSP00000276571	P		Seeded From UniProt	complete
involved_in	GO:0051464	positive regulation of cortisol secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06850 ensembl:ENSP00000276571	P		Seeded From UniProt	complete
involved_in	GO:0051461	positive regulation of corticotropin secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06850 ensembl:ENSP00000276571	P		Seeded From UniProt	complete
involved_in	GO:0006954	inflammatory response	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06850 ensembl:ENSP00000276571	P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06850 ensembl:ENSP00000276571	C		Seeded From UniProt	complete
involved_in	GO:0001963	synaptic transmission, dopaminergic	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P06850 ensembl:ENSP00000276571	P		Seeded From UniProt	complete
involved_in	GO:0035641	locomotory exploration behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8CIT0 ensembl:ENSMUSP00000061185	P		Seeded From UniProt	complete
involved_in	GO:0030325	adrenal gland development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8CIT0 ensembl:ENSMUSP00000061185	P		Seeded From UniProt	complete
involved_in	GO:0030324	lung development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8CIT0 ensembl:ENSMUSP00000061185	P		Seeded From UniProt	complete
involved_in	GO:0006954	inflammatory response	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8CIT0 ensembl:ENSMUSP00000061185	P		Seeded From UniProt	complete
involved_in	GO:0006704	glucocorticoid biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8CIT0 ensembl:ENSMUSP00000061185	P		Seeded From UniProt	complete
enables	GO:0005179	hormone activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000187 InterPro:IPR003620	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000187 InterPro:IPR003620	C		Seeded From UniProt	complete
involved_in	GO:2000379	positive regulation of reactive oxygen species metabolic process	PMID:18786646^[3]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0072592	oxygen metabolic process	PMID:18620026^[4]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Madison, FN et al. (2008) Sex differences in plasma corticosterone release in undisturbed chickens (Gallus gallus) in response to arginine vasotocin and corticotropin releasing hormone. Gen. Comp. Endocrinol. 155 566-73 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 Tachibana, T et al. (2004) Comparison of brain arginine-vasotocin and corticotrophin-releasing factor for physiological responses in chicks. Neurosci. Lett. 360 165-9 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 Mujahid, A & Furuse, M (2008) Central administration of corticotropin-releasing factor induces tissue specific oxidative damage in chicks. Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. 151 664-9 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 Mujahid, A & Furuse, M (2008) Central administration of corticotropin-releasing factor induces thermogenesis by changes in mitochondrial bioenergetics in neonatal chicks. Neuroscience 155 845-51 PubMed GONUTS page
↑ Petrusz, P et al. (1983) Corticotropin-releasing factor (CRF)-like immunoreactivity in the vertebrate endocrine pancreas. Proc. Natl. Acad. Sci. U.S.A. 80 1721-5 PubMed GONUTS page
↑ ^6.0 ^6.1 Kamisoyama, H et al. (2009) Corticotropin-releasing factor is a downstream mediator of the beta-melanocyte-stimulating hormone-induced anorexigenic pathway in chicks. Neurosci. Lett. 458 102-5 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 ^7.3 ^7.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:17936761-1] Madison, FN et al. (2008) Sex differences in plasma corticosterone release in undisturbed chickens (Gallus gallus) in response to arginine vasotocin and corticotropin releasing hormone. Gen. Comp. Endocrinol. 155 566-73 PubMed GONUTS page

[PMID:15082159-2] 2.0 ^2.1 ^2.2 Tachibana, T et al. (2004) Comparison of brain arginine-vasotocin and corticotrophin-releasing factor for physiological responses in chicks. Neurosci. Lett. 360 165-9 PubMed GONUTS page

[PMID:18786646-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 Mujahid, A & Furuse, M (2008) Central administration of corticotropin-releasing factor induces tissue specific oxidative damage in chicks. Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. 151 664-9 PubMed GONUTS page

[PMID:18620026-4] 4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 Mujahid, A & Furuse, M (2008) Central administration of corticotropin-releasing factor induces thermogenesis by changes in mitochondrial bioenergetics in neonatal chicks. Neuroscience 155 845-51 PubMed GONUTS page

[PMID:6340106-5] Petrusz, P et al. (1983) Corticotropin-releasing factor (CRF)-like immunoreactivity in the vertebrate endocrine pancreas. Proc. Natl. Acad. Sci. U.S.A. 80 1721-5 PubMed GONUTS page

[PMID:19393716-6] 6.0 ^6.1 Kamisoyama, H et al. (2009) Corticotropin-releasing factor is a downstream mediator of the beta-melanocyte-stimulating hormone-induced anorexigenic pathway in chicks. Neurosci. Lett. 458 102-5 PubMed GONUTS page

[PMID:21873635-7] 7.0 ^7.1 ^7.2 ^7.3 ^7.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:Q703P0

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