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CHICK:Q6IT44

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) IL18 (ECO:0000313 with Ensembl:ENSGALP00000012772)
Protein Name(s) Interleukin 18 (ECO:0000313 with EMBL:AAT40993.2)

Interleukin-18 (ECO:0000313 with Ensembl:ENSGALP00000012772)

External Links
UniProt Q6IT44
EMBL AADN03008267
AY628648
AY920749
UniGene Gga.17593
Ensembl ENSGALT00000012787
GeneTree ENSGT00390000001053
HOVERGEN HBG102119
OMA AFKFEYS
OrthoDB EOG7SR4NN
TreeFam TF336297
Reactome REACT_197474
Proteomes UP000000539
GO GO:0005615
GO:0070062
GO:0001525
GO:0071407
GO:0006954
GO:0031663
GO:0000165
GO:0030101
GO:0042104
GO:0010628
GO:0032725
GO:0032729
GO:0032740
GO:0032819
GO:0042346
GO:0051142
GO:0030155
GO:0042088
InterPro IPR008996
IPR015529
IPR000975
PANTHER PTHR11326
Pfam PF00340
PIRSF PIRSF015162
PRINTS PR01933
SUPFAM SSF50353

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0035710

CD4-positive, alpha-beta T cell activation

PMID:12902481[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0050671

positive regulation of lymphocyte proliferation

PMID:12902481[1]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(CL:0000492)

Seeded From UniProt

complete

involved_in

GO:1902715

positive regulation of interferon-gamma secretion

PMID:12902481[1]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(CL:0000492)

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005125

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005125

P

Seeded From UniProt

complete

enables

GO:0005125

cytokine activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000975

F

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000975

C

Seeded From UniProt

complete

involved_in

GO:0006954

inflammatory response

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000975

P

Seeded From UniProt

complete

involved_in

GO:0006955

immune response

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000975

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0202

C

Seeded From UniProt

complete

enables

GO:0005125

cytokine activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0202

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000483752

C

Seeded From UniProt

complete

involved_in

GO:0006954

inflammatory response

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000483752

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Göbel, TW et al. (2003) IL-18 stimulates the proliferation and IFN-gamma release of CD4+ T cells in the chicken: conservation of a Th1-like system in a nonmammalian species. J. Immunol. 171 1809-15 PubMed GONUTS page