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CHICK:Q5ZK76

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) No Information Provided.
Protein Name(s) alpha-1,2-Mannosidase (ECO:0000256 with RuleBase:RU361193)
External Links
UniProt Q5ZK76
EMBL AJ720208
RefSeq NP_001006143.1
UniGene Gga.17487
ProteinModelPortal Q5ZK76
STRING 9031.ENSGALP00000013528
CAZy GH47
PaxDb Q5ZK76
GeneID 416110
KEGG gga:416110
CTD 9695
eggNOG NOG307610
HOGENOM HOG000004833
HOVERGEN HBG051158
KO K10084
PhylomeDB Q5ZK76
NextBio 20819619
PRO PR:Q5ZK76
GO GO:0016020
GO:0005509
GO:0004571
Gene3D 1.50.10.50
InterPro IPR001382
PANTHER PTHR11742
Pfam PF01532
PRINTS PR00747
SUPFAM SSF48225

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0004571

mannosyl-oligosaccharide 1,2-alpha-mannosidase activity

PMID:25092655[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

has_direct_input:(CHEBI:60627)

Seeded From UniProt

complete

involved_in

GO:1904382

mannose trimming involved in glycoprotein ERAD pathway

PMID:25092655[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0044322

endoplasmic reticulum quality control compartment

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0036510

C

Seeded From UniProt

complete

involved_in

GO:1904382

mannose trimming involved in glycoprotein ERAD pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q92611
ensembl:ENSP00000256497

P

Seeded From UniProt

complete

involved_in

GO:1904154

positive regulation of retrograde protein transport, ER to cytosol

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q92611
ensembl:ENSP00000256497

P

Seeded From UniProt

complete

involved_in

GO:0097466

ubiquitin-dependent glycoprotein ERAD pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q92611
ensembl:ENSP00000256497

P

Seeded From UniProt

complete

enables

GO:0051787

misfolded protein binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q92611
ensembl:ENSP00000256497

F

Seeded From UniProt

complete

part_of

GO:0016235

aggresome

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q92611
ensembl:ENSP00000256497

C

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q92611
ensembl:ENSP00000256497

C

Seeded From UniProt

complete

enables

GO:0004571

mannosyl-oligosaccharide 1,2-alpha-mannosidase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q92611
ensembl:ENSP00000256497

F

Seeded From UniProt

complete

involved_in

GO:1904154

positive regulation of retrograde protein transport, ER to cytosol

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q925U4
ensembl:ENSMUSP00000086565

P

Seeded From UniProt

complete

involved_in

GO:0036510

trimming of terminal mannose on C branch

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q925U4
ensembl:ENSMUSP00000086565

P

Seeded From UniProt

complete

involved_in

GO:0030433

ubiquitin-dependent ERAD pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q925U4
ensembl:ENSMUSP00000086565

P

Seeded From UniProt

complete

part_of

GO:0030176

integral component of endoplasmic reticulum membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q925U4
ensembl:ENSMUSP00000086565

C

Seeded From UniProt

complete

enables

GO:0004571

mannosyl-oligosaccharide 1,2-alpha-mannosidase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q925U4
ensembl:ENSMUSP00000086565

F

Seeded From UniProt

complete

part_of

GO:0016235

aggresome

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:A0A024R2D5
ensembl:ENSP00000256497

C

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012341

F

Seeded From UniProt

complete

enables

GO:0004571

mannosyl-oligosaccharide 1,2-alpha-mannosidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001382
InterPro:IPR036026

F

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001382
InterPro:IPR036026

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001382
InterPro:IPR036026

C

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

enables

GO:0016798

hydrolase activity, acting on glycosyl bonds

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0326

F

Seeded From UniProt

complete

involved_in

GO:0008152

metabolic process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0326

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Ninagawa, S et al. (2014) EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step. J. Cell Biol. 206 347-56 PubMed GONUTS page