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CHICK:Q4VU66

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) ZP3 (synonyms: ZPC)
Protein Name(s) Zona pellucida sperm-binding protein 3

Sperm receptor Zona pellucida C protein Zona pellucida glycoprotein 3 Zp-3 Processed zona pellucida sperm-binding protein 3

External Links
UniProt P79762
EMBL D89097
AY628608
AY628609
AY628610
AY628611
AY628612
AY628613
AY628614
AY628615
AY628616
AY628617
AY628618
AY628619
AY628620
AY628621
AY628622
AY628623
AY628624
AY628625
AY628626
AY628627
AY628628
AY628629
AY628630
AB031033
RefSeq NP_989720.3
UniGene Gga.7210
PDB 3NK3
3NK4
PDBsum 3NK3
3NK4
STRING 9031.ENSGALP00000002368
PaxDb P79762
Ensembl ENSGALT00000002370
GeneID 378906
KEGG gga:378906
CTD 7784
eggNOG NOG43042
GeneTree ENSGT00530000063482
HOVERGEN HBG007985
InParanoid P79762
OMA VECHYPR
OrthoDB EOG79KPFT
PhylomeDB P79762
TreeFam TF331369
Reactome REACT_197139
NextBio 20813875
Proteomes UP000000539
GO GO:0016021
GO:0005886
GO:0005578
GO:0042802
GO:0007338
InterPro IPR001507
IPR017977
Pfam PF00100
PRINTS PR00023
SMART SM00241
PROSITE PS00682
PS51034

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0045177

apical part of cell

PMID:9780332[1]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0000501)

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:9780332[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005623

cell

PMID:10103002[2]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0000501)

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:10103002[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O73670

C

Seeded From UniProt

complete

involved_in

GO:0033574

response to testosterone

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O73670

P

Seeded From UniProt

complete

involved_in

GO:0032570

response to progesterone

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O73670

P

Seeded From UniProt

complete

involved_in

GO:2000344

positive regulation of acrosome reaction

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:99215
PANTHER:PTN000171662
UniProtKB:P21754

P

Seeded From UniProt

complete

involved_in

GO:0035803

egg coat formation

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:99215
PANTHER:PTN000171662

P

Seeded From UniProt

complete

enables

GO:0032190

acrosin binding

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000171662
UniProtKB:P21754

F

Seeded From UniProt

complete

involved_in

GO:0007339

binding of sperm to zona pellucida

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:99215
PANTHER:PTN000171662
UniProtKB:P21754
UniProtKB:P48830
UniProtKB:P48831

P

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:20970175[4]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P79762

F

Seeded From UniProt

complete

involved_in

GO:0007339

binding of sperm to zona pellucida

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR040196

P

Seeded From UniProt

complete

involved_in

GO:0035803

egg coat formation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR040196

P

Seeded From UniProt

complete

enables

GO:0035804

structural constituent of egg coat

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR040196

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

involved_in

GO:0007338

single fertilization

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0278

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Waclawek, M et al. (1998) The chicken homologue of zona pellucida protein-3 is synthesized by granulosa cells. Biol. Reprod. 59 1230-9 PubMed GONUTS page
  2. 2.0 2.1 Takeuchi, Y et al. (1999) A 42-kDa glycoprotein from chicken egg-envelope, an avian homolog of the ZPC family glycoproteins in mammalian Zona pellucida. Its first identification, cDNA cloning and granulosa cell-specific expression. Eur. J. Biochem. 260 736-42 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  4. Han, L et al. (2010) Insights into egg coat assembly and egg-sperm interaction from the X-ray structure of full-length ZP3. Cell 143 404-15 PubMed GONUTS page