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CHICK:PUR9
Contents
| Species (Taxon ID) | Gallus gallus (Chicken). (9031) | |
| Gene Name(s) | ATIC (synonyms: PURH) | |
| Protein Name(s) | Bifunctional purine biosynthesis protein PURH
Phosphoribosylaminoimidazolecarboxamide formyltransferase 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase AICAR transformylase IMP cyclohydrolase ATIC IMP synthase Inosinicase | |
| External Links | ||
| UniProt | P31335 | |
| EMBL | S64492 | |
| PIR | JQ1281 | |
| RefSeq | NP_990509.1 | |
| UniGene | Gga.4556 | |
| PDB | 1G8M 1M9N 1OZ0 1THZ 2B1G 2B1I 2IU0 2IU3 | |
| PDBsum | 1G8M 1M9N 1OZ0 1THZ 2B1G 2B1I 2IU0 2IU3 | |
| ProteinModelPortal | P31335 | |
| SMR | P31335 | |
| PaxDb | P31335 | |
| PRIDE | P31335 | |
| GeneID | 396091 | |
| KEGG | gga:396091 | |
| CTD | 471 | |
| eggNOG | COG0138 | |
| HOGENOM | HOG000230372 | |
| HOVERGEN | HBG006912 | |
| InParanoid | P31335 | |
| KO | K00602 | |
| PhylomeDB | P31335 | |
| Reactome | REACT_116007 | |
| UniPathway | UPA00074 UPA00074 | |
| EvolutionaryTrace | P31335 | |
| NextBio | 20816149 | |
| PRO | PR:P31335 | |
| Proteomes | UP000000539 | |
| GO | GO:0005829 GO:0003937 GO:0004643 GO:0042803 GO:0006189 GO:0055086 GO:0006144 GO:0044281 | |
| Gene3D | 1.10.287.440 3.40.140.20 3.40.50.1380 | |
| HAMAP | MF_00139 | |
| InterPro | IPR024051 IPR024050 IPR002695 IPR016193 IPR011607 | |
| PANTHER | PTHR11692 | |
| Pfam | PF01808 PF02142 | |
| PIRSF | PIRSF000414 | |
| SMART | SM00798 SM00851 | |
| SUPFAM | SSF52335 SSF53927 | |
| TIGRFAMs | TIGR00355 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0042803 |
protein homodimerization activity |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003824 |
catalytic activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003937 |
IMP cyclohydrolase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004643 |
phosphoribosylaminoimidazolecarboxamide formyltransferase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006164 |
purine nucleotide biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003937 |
IMP cyclohydrolase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004643 |
phosphoribosylaminoimidazolecarboxamide formyltransferase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006189 |
'de novo' IMP biosynthetic process |
Reactome:R-GGA-419140 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
Reactome:R-GGA-419254 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
|
involved_in |
GO:0006164 |
purine nucleotide biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003824 |
catalytic activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008152 |
metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006189 |
'de novo' IMP biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00074 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Greasley, SE et al. (2001) Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis. Nat. Struct. Biol. 8 402-6 PubMed GONUTS page