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CHICK:PUR8

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) ADSL
Protein Name(s) Adenylosuccinate lyase

ASL Adenylosuccinase ASase

External Links
UniProt P21265
EMBL AY665559
EU049886
M37901
PIR A35291
RefSeq NP_990860.1
UniGene Gga.2721
ProteinModelPortal P21265
PaxDb P21265
PRIDE P21265
GeneID 396540
KEGG gga:396540
CTD 158
eggNOG COG0015
HOGENOM HOG000033915
HOVERGEN HBG000214
InParanoid P21265
KO K01756
PhylomeDB P21265
Reactome REACT_115540
REACT_116007
UniPathway UPA00074
UPA00075
NextBio 20816576
PRO PR:P21265
Proteomes UP000000539
GO GO:0005829
GO:0070626
GO:0004018
GO:0044208
GO:0006189
GO:0006167
GO:0055086
GO:0006144
GO:0044281
Gene3D 1.10.275.10
InterPro IPR019468
IPR024083
IPR020557
IPR000362
IPR022761
IPR008948
IPR004769
PANTHER PTHR11444
Pfam PF10397
PF00206
PRINTS PR00149
SMART SM00998
SUPFAM SSF48557
TIGRFAMs TIGR00928
PROSITE PS00163

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0070626

(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000154581
PomBase:SPBC14F5.09c
RGD:1307617

F

Seeded From UniProt

complete

involved_in

GO:0044208

'de novo' AMP biosynthetic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000154581
PomBase:SPBC14F5.09c

P

Seeded From UniProt

complete

enables

GO:0004018

N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000154581
PomBase:SPBC14F5.09c
RGD:1307617
SGD:S000004351
UniProtKB:P12047
UniProtKB:P30566

F

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008948
InterPro:IPR020557

F

Seeded From UniProt

complete

enables

GO:0004018

N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004769

F

Seeded From UniProt

complete

involved_in

GO:0009152

purine ribonucleotide biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004769

P

Seeded From UniProt

complete

enables

GO:0004018

N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:4.3.2.2

F

Seeded From UniProt

complete

enables

GO:0070626

(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:4.3.2.2

F

Seeded From UniProt

complete

enables

GO:0070626

(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity

Reactome:R-GGA-419255

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006189

'de novo' IMP biosynthetic process

Reactome:R-GGA-419140

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

Reactome:R-GGA-419255

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0016829

lyase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0456

F

Seeded From UniProt

complete

involved_in

GO:0006164

purine nucleotide biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0658

P

Seeded From UniProt

complete

involved_in

GO:0044208

'de novo' AMP biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00075

P

Seeded From UniProt

complete

involved_in

GO:0006189

'de novo' IMP biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00074

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page