CHICK:PUR6

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	AIRC
Protein Name(s)	Multifunctional protein ADE2 Phosphoribosylaminoimidazole-succinocarboxamide synthase SAICAR synthetase Phosphoribosylaminoimidazole carboxylase AIR carboxylase AIRC
External Links
UniProt	P38024
EMBL	M31764 L12533
PIR	A35641
RefSeq	NP_990855.1
UniGene	Gga.3058
ProteinModelPortal	P38024
SMR	P38024
BioGrid	676778
STRING	9031.ENSGALP00000022269
BindingDB	P38024
ChEMBL	CHEMBL5312
PaxDb	P38024
PRIDE	P38024
GeneID	396534
KEGG	gga:396534
CTD	10606
eggNOG	COG0041
HOGENOM	HOG000082628
HOVERGEN	HBG008335
InParanoid	P38024
KO	K01587
OrthoDB	EOG725DHT
PhylomeDB	P38024
TreeFam	TF106384
Reactome	REACT_116007 REACT_239822
UniPathway	UPA00074 UPA00074
NextBio	20816570
PRO	PR:P38024
Proteomes	UP000000539
ExpressionAtlas	P38024
GO	GO:0005829 GO:0070062 GO:0016020 GO:0005524 GO:0004638 GO:0004639 GO:0006189 GO:0055086 GO:0006144 GO:0044281
Gene3D	3.30.470.20 3.40.50.7700
HAMAP	MF_00137
InterPro	IPR013816 IPR000031 IPR028923 IPR018236
Pfam	PF00731 PF01259
SMART	SM01001
SUPFAM	SSF52255
TIGRFAMs	TIGR01162
PROSITE	PS01057 PS01058

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
part_of	GO:0005829	cytosol		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10791 PANTHER:PTN000176641	C		Seeded From UniProt	complete
enables	GO:0004639	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR018236	F		Seeded From UniProt	complete
involved_in	GO:0006164	purine nucleotide biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR018236	P		Seeded From UniProt	complete
involved_in	GO:0006189	'de novo' IMP biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000031 InterPro:IPR033626	P		Seeded From UniProt	complete
enables	GO:0004638	phosphoribosylaminoimidazole carboxylase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:4.1.1.21	F		Seeded From UniProt	complete
enables	GO:0043727	5-amino-4-imidazole carboxylate lyase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:4.1.1.21	F		Seeded From UniProt	complete
enables	GO:0004639	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:6.3.2.6	F		Seeded From UniProt	complete
involved_in	GO:0006189	'de novo' IMP biosynthetic process	Reactome:R-GGA-419140	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	Reactome:R-GGA-419223 Reactome:R-GGA-419214	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
involved_in	GO:0008152	metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0511	P		Seeded From UniProt	complete
enables	GO:0016829	lyase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0456	F		Seeded From UniProt	complete
enables	GO:0016831	carboxy-lyase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0210	F		Seeded From UniProt	complete
enables	GO:0003824	catalytic activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0511	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F		Seeded From UniProt	complete
enables	GO:0016874	ligase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0436	F		Seeded From UniProt	complete
involved_in	GO:0006164	purine nucleotide biosynthetic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0658	P		Seeded From UniProt	complete
involved_in	GO:0006189	'de novo' IMP biosynthetic process	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00074	P		Seeded From UniProt	complete
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References

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