CHICK:PUR2

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	GART
Protein Name(s)	Trifunctional purine biosynthetic protein adenosine-3 Phosphoribosylamine--glycine ligase Glycinamide ribonucleotide synthetase GARS Phosphoribosylglycinamide synthetase Phosphoribosylformylglycinamidine cyclo-ligase AIR synthase AIRS Phosphoribosyl-aminoimidazole synthetase Phosphoribosylglycinamide formyltransferase 5'-phosphoribosylglycinamide transformylase GAR transformylase GART
External Links
UniProt	P21872
EMBL	X56339 X54200
PIR	S12617
RefSeq	NP_001001469.1
UniGene	Gga.4704
ProteinModelPortal	P21872
SMR	P21872
STRING	9031.ENSGALP00000025711
PaxDb	P21872
GeneID	395315
KEGG	gga:395315
CTD	2618
eggNOG	COG0151
HOGENOM	HOG000030315
HOVERGEN	HBG008333
InParanoid	P21872
KO	K11787
PhylomeDB	P21872
Reactome	REACT_116007
UniPathway	UPA00074 UPA00074 UPA00074
NextBio	20815400
PRO	PR:P21872
Proteomes	UP000000539
GO	GO:0005829 GO:0005524 GO:0046872 GO:0008168 GO:0004637 GO:0004641 GO:0004644 GO:0006189 GO:0055086 GO:0009113 GO:0006144 GO:0044281
Gene3D	3.30.1330.10 3.30.1490.20 3.30.470.20 3.40.50.170 3.40.50.20 3.90.600.10 3.90.650.10
HAMAP	MF_00138 MF_00741 MF_01930
InterPro	IPR010918 IPR000728 IPR011761 IPR013815 IPR013816 IPR002376 IPR001555 IPR016185 IPR020561 IPR000115 IPR020560 IPR020559 IPR020562 IPR004733 IPR016188 IPR004607 IPR011054
Pfam	PF00586 PF02769 PF00551 PF01071 PF02843 PF02844
SUPFAM	SSF51246 SSF52440 SSF53328 SSF55326 SSF56042
TIGRFAMs	TIGR00877 TIGR00878 TIGR00639
PROSITE	PS50975 PS00184 PS00373

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0046084	adenine biosynthetic process	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000055158 UniProtKB:A0A1D8PE67	P	Seeded From UniProt	complete
involved_in	GO:0006164	purine nucleotide biosynthetic process	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000055158 TAIR:locus:2097203	P	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10798 PANTHER:PTN000055158	C	Seeded From UniProt	complete
enables	GO:0004641	phosphoribosylformylglycinamidine cyclo-ligase activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10798 FB:FBgn0000053 PANTHER:PTN000055158 PomBase:SPBC405.01 RGD:1308717 TAIR:locus:2097203	F	Seeded From UniProt	complete
enables	GO:0004637	phosphoribosylamine-glycine ligase activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000053 PANTHER:PTN000055158 PomBase:SPBC405.01 RGD:1308717	F	Seeded From UniProt	complete
enables	GO:0004637	phosphoribosylamine-glycine ligase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000115 InterPro:IPR020559 InterPro:IPR020560 InterPro:IPR020562 InterPro:IPR037123	F	Seeded From UniProt	complete
enables	GO:0004641	phosphoribosylformylglycinamidine cyclo-ligase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004733	F	Seeded From UniProt	complete
enables	GO:0004644	phosphoribosylglycinamide formyltransferase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004607	F	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011761 InterPro:IPR013815	F	Seeded From UniProt	complete
involved_in	GO:0006189	'de novo' IMP biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004607 InterPro:IPR004733	P	Seeded From UniProt	complete
involved_in	GO:0009058	biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002376 InterPro:IPR036477	P	Seeded From UniProt	complete
involved_in	GO:0009113	purine nucleobase biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000115 InterPro:IPR020559 InterPro:IPR020560 InterPro:IPR020562 InterPro:IPR037123	P	Seeded From UniProt	complete
enables	GO:0016742	hydroxymethyl-, formyl- and related transferase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002376 InterPro:IPR036477	F	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011761	F	Seeded From UniProt	complete
enables	GO:0004641	phosphoribosylformylglycinamidine cyclo-ligase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:6.3.3.1	F	Seeded From UniProt	complete
enables	GO:0004644	phosphoribosylglycinamide formyltransferase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.1.2.2	F	Seeded From UniProt	complete
enables	GO:0004637	phosphoribosylamine-glycine ligase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:6.3.4.13	F	Seeded From UniProt	complete
involved_in	GO:0006189	'de novo' IMP biosynthetic process	Reactome:R-GGA-419140	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	Reactome:R-GGA-419157 Reactome:R-GGA-419153 Reactome:R-GGA-419145	ECO:0000304	author statement supported by traceable reference used in manual assertion		C	Seeded From UniProt	complete
enables	GO:0004644	phosphoribosylglycinamide formyltransferase activity	Reactome:R-GGA-419145	ECO:0000304	author statement supported by traceable reference used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0004641	phosphoribosylformylglycinamidine cyclo-ligase activity	Reactome:R-GGA-419157	ECO:0000304	author statement supported by traceable reference used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0004637	phosphoribosylamine-glycine ligase activity	Reactome:R-GGA-419153	ECO:0000304	author statement supported by traceable reference used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F	Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F	Seeded From UniProt	complete
involved_in	GO:0006164	purine nucleotide biosynthetic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0658	P	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F	Seeded From UniProt	complete
involved_in	GO:0008152	metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0511	P	Seeded From UniProt	complete
enables	GO:0016874	ligase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0436	F	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F	Seeded From UniProt	complete
enables	GO:0003824	catalytic activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0511	F	Seeded From UniProt	complete
involved_in	GO:0006189	'de novo' IMP biosynthetic process	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00074	P	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:PUR2

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