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CHICK:PGFRA
Contents
Species (Taxon ID) | Gallus gallus (Chicken). (9031) | |
Gene Name(s) | PDGFRA | |
Protein Name(s) | Platelet-derived growth factor receptor alpha
PDGF-R-alpha PDGFR-alpha Alpha platelet-derived growth factor receptor Alpha-type platelet-derived growth factor receptor | |
External Links | ||
UniProt | Q9PUF6 | |
EMBL | AF188842 | |
RefSeq | NP_990080.1 | |
UniGene | Gga.274 | |
ProteinModelPortal | Q9PUF6 | |
SMR | Q9PUF6 | |
STRING | 9031.ENSGALP00000009175 | |
PaxDb | Q9PUF6 | |
PRIDE | Q9PUF6 | |
GeneID | 395509 | |
KEGG | gga:395509 | |
CTD | 5156 | |
eggNOG | COG0515 | |
HOGENOM | HOG000112009 | |
HOVERGEN | HBG004335 | |
InParanoid | Q9PUF6 | |
KO | K04363 | |
PhylomeDB | Q9PUF6 | |
NextBio | 20815588 | |
PRO | PR:Q9PUF6 | |
Proteomes | UP000000539 | |
GO | GO:0016021 GO:0005886 GO:0005524 GO:0005018 GO:0006935 GO:0048704 | |
Gene3D | 2.60.40.10 | |
InterPro | IPR007110 IPR013783 IPR013098 IPR003599 IPR011009 IPR027290 IPR000719 IPR017441 IPR001245 IPR008266 IPR020635 IPR016243 IPR001824 | |
PANTHER | PTHR24416:SF52 | |
Pfam | PF07679 PF07714 | |
PIRSF | PIRSF500950 PIRSF000615 | |
SMART | SM00409 SM00219 | |
SUPFAM | SSF56112 | |
PROSITE | PS50835 PS00107 PS50011 PS00109 PS00240 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
part_of |
GO:0005929 |
cilium |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0048704 |
embryonic skeletal system morphogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0070374 |
positive regulation of ERK1 and ERK2 cascade |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1339758 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0048407 |
platelet-derived growth factor binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:97530 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0043410 |
positive regulation of MAPK cascade |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003733 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0043235 |
receptor complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0015380 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0008284 |
positive regulation of cell population proliferation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1339758 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003366 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003366 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0005018 |
platelet-derived growth factor alpha-receptor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:97530 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004714 |
transmembrane receptor protein tyrosine kinase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003733 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0002244 |
hematopoietic progenitor cell differentiation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:95559 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0018108 |
peptidyl-tyrosine phosphorylation |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004714 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0018108 |
peptidyl-tyrosine phosphorylation |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004713 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0018108 |
peptidyl-tyrosine phosphorylation |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0004714 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0018108 |
peptidyl-tyrosine phosphorylation |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004713 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0018108 |
peptidyl-tyrosine phosphorylation |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004714 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0035790 |
platelet-derived growth factor receptor-alpha signaling pathway |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005018 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0035790 |
platelet-derived growth factor receptor-alpha signaling pathway |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005018 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0004672 |
protein kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004713 |
protein tyrosine kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004714 |
transmembrane receptor protein tyrosine kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005018 |
platelet-derived growth factor alpha-receptor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006468 |
protein phosphorylation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000719 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0048008 |
platelet-derived growth factor receptor signaling pathway |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0004714 |
transmembrane receptor protein tyrosine kinase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016301 |
kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007275 |
multicellular organism development |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0004713 |
protein tyrosine kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0042995 |
cell projection |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006935 |
chemotaxis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005929 |
cilium |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Pickett, EA et al. (2008) Disruption of PDGFRalpha-initiated PI3K activation and migration of somite derivatives leads to spina bifida. Development 135 589-98 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 2.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
c
p
- GO:0018108 ! peptidyl-tyrosine phosphorylation
- Phasianidae
- Phasianinae
- GO:0016310 ! phosphorylation
- GO:0005886 ! plasma membrane
- GO:0048008 ! platelet-derived growth factor receptor signaling pathway
- GO:0035790 ! platelet-derived growth factor receptor-alpha signaling pathway
- GO:0048407 ! platelet-derived growth factor binding
- GO:0005018 ! platelet-derived growth factor alpha-receptor activity
- GO:0008284 ! positive regulation of cell population proliferation
- GO:0070374 ! positive regulation of ERK1 and ERK2 cascade
- GO:0043410 ! positive regulation of MAPK cascade
- GO:0004672 ! protein kinase activity
- GO:0006468 ! protein phosphorylation
- GO:0004713 ! protein tyrosine kinase activity
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