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CHICK:P79773

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) IRS-1 (ECO:0000313 with EMBL:AAC60050.1)
Protein Name(s) Insulin receptor substrate 1 (ECO:0000313 with EMBL:AAC60050.1)
External Links
UniProt P79773
EMBL U43502
PIR JC5209
RefSeq NP_001026741.1
UniGene Gga.32082
ProteinModelPortal P79773
SMR P79773
STRING 9031.ENSGALP00000007937
PaxDb P79773
PRIDE P79773
GeneID 429262
KEGG gga:429262
CTD 3667
eggNOG NOG81285
HOVERGEN HBG000542
KO K16172
PhylomeDB P79773
NextBio 20830017
PRO PR:P79773
Gene3D 2.30.29.30
InterPro IPR002404
IPR001849
IPR011993
Pfam PF02174
PF00169
PRINTS PR00628
SMART SM00233
SM00310
PROSITE PS51064
PS50003

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0046628

positive regulation of insulin receptor signaling pathway

PMID:9605520[1]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P35568

P

positively_regulates:(GO:0046326)

Seeded From UniProt

complete

involved_in

GO:0048009

insulin-like growth factor receptor signaling pathway

PMID:9605520[1]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P35568

P

Seeded From UniProt

complete

involved_in

GO:0046676

negative regulation of insulin secretion

PMID:9605520[1]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P35568

P

Seeded From UniProt

complete

involved_in

GO:0046326

positive regulation of glucose import

PMID:9605520[1]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P35568

P

Seeded From UniProt

complete

involved_in

GO:0045725

positive regulation of glycogen biosynthetic process

PMID:9605520[1]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P35568

P

Seeded From UniProt

complete

involved_in

GO:0032868

response to insulin

PMID:9605520[1]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P35568

P

Seeded From UniProt

complete

involved_in

GO:0032000

positive regulation of fatty acid beta-oxidation

PMID:9605520[1]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P35568

P

Seeded From UniProt

complete

involved_in

GO:0014065

phosphatidylinositol 3-kinase signaling

PMID:9605520[1]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P35568

P

Seeded From UniProt

complete

involved_in

GO:0010907

positive regulation of glucose metabolic process

PMID:9605520[1]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P35568

P

Seeded From UniProt

complete

involved_in

GO:0008286

insulin receptor signaling pathway

PMID:9605520[1]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P35568

P

Seeded From UniProt

complete

enables

GO:0005158

insulin receptor binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039011

F

Seeded From UniProt

complete

involved_in

GO:0008286

insulin receptor signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039011

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Taouis, M et al. (1998) Insulin receptor substrate 1 antisense expression in an hepatoma cell line reduces cell proliferation and induces overexpression of the Src homology 2 domain and collagen protein (SHC). Mol. Cell. Endocrinol. 137 177-86 PubMed GONUTS page