CHICK:O93466

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	cRac1B (ECO:0000313 with EMBL:AAC18961.1)
Protein Name(s)	GTPase cRac1B (ECO:0000313 with EMBL:AAC18961.1)
External Links
UniProt	O93466
EMBL	U79756
RefSeq	NP_990347.1
UniGene	Gga.2936
ProteinModelPortal	O93466
SMR	O93466
STRING	9031.ENSGALP00000034098
PRIDE	O93466
GeneID	395870
KEGG	gga:395870
CTD	5881
eggNOG	COG1100
HOGENOM	HOG000233974
HOVERGEN	HBG009351
KO	K07861
OrthoDB	EOG764747
PhylomeDB	O93466
NextBio	20815937
GO	GO:0005622 GO:0016020 GO:0005525 GO:0007264
Gene3D	3.40.50.300
InterPro	IPR027417 IPR005225 IPR001806 IPR003578
Pfam	PF00071
PRINTS	PR00449
SMART	SM00174
SUPFAM	SSF52540
TIGRFAMs	TIGR00231
PROSITE	PS51420

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
enables	GO:0044877	protein-containing complex binding	PMID:11950598^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	has_input:(UniProtKB:O55043) has_input:(UniProtKB:Q13153) has_input:(UniProtKB:Q9DE64)	Seeded From UniProt	complete
part_of	GO:0070852	cell body fiber	PMID:9254684^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0010009)	Seeded From UniProt	complete
involved_in	GO:0048812	neuron projection morphogenesis	PMID:9700168^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(CL:0009004)	Seeded From UniProt	complete
involved_in	GO:0031532	actin cytoskeleton reorganization	PMID:9700168^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(CL:0000057)	Seeded From UniProt	complete
involved_in	GO:0051932	synaptic transmission, GABAergic	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P60764 ensembl:ENSMUSP00000018156	P		Seeded From UniProt	complete
involved_in	GO:0050905	neuromuscular process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P60764 ensembl:ENSMUSP00000018156	P		Seeded From UniProt	complete
involved_in	GO:0050885	neuromuscular process controlling balance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P60764 ensembl:ENSMUSP00000018156	P		Seeded From UniProt	complete
involved_in	GO:0048873	homeostasis of number of cells within a tissue	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P60764 ensembl:ENSMUSP00000018156	P		Seeded From UniProt	complete
involved_in	GO:0031175	neuron projection development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P60764 ensembl:ENSMUSP00000018156	P		Seeded From UniProt	complete
involved_in	GO:0022604	regulation of cell morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P60764 ensembl:ENSMUSP00000018156	P		Seeded From UniProt	complete
involved_in	GO:0021894	cerebral cortex GABAergic interneuron development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P60764 ensembl:ENSMUSP00000018156	P		Seeded From UniProt	complete
involved_in	GO:0014041	regulation of neuron maturation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P60764 ensembl:ENSMUSP00000018156	P		Seeded From UniProt	complete
involved_in	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P60763 ensembl:ENSP00000304283	P		Seeded From UniProt	complete
part_of	GO:0071944	cell periphery	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P60763 ensembl:ENSP00000304283	C		Seeded From UniProt	complete
part_of	GO:0048471	perinuclear region of cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P60763 ensembl:ENSP00000304283	C		Seeded From UniProt	complete
enables	GO:0048306	calcium-dependent protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P60763 ensembl:ENSP00000304283	F		Seeded From UniProt	complete
part_of	GO:0043025	neuronal cell body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P60763 ensembl:ENSP00000304283	C		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P60763 ensembl:ENSP00000304283	C		Seeded From UniProt	complete
involved_in	GO:0033630	positive regulation of cell adhesion mediated by integrin	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P60763 ensembl:ENSP00000304283	P		Seeded From UniProt	complete
part_of	GO:0031941	filamentous actin	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P60763 ensembl:ENSP00000304283	C		Seeded From UniProt	complete
part_of	GO:0030426	growth cone	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P60763 ensembl:ENSP00000304283	C		Seeded From UniProt	complete
involved_in	GO:0030036	actin cytoskeleton organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P60763 ensembl:ENSP00000304283	P		Seeded From UniProt	complete
involved_in	GO:0030031	cell projection assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P60763 ensembl:ENSP00000304283	P		Seeded From UniProt	complete
part_of	GO:0012505	endomembrane system	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P60763 ensembl:ENSP00000304283	C		Seeded From UniProt	complete
enables	GO:0003924	GTPase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P60763 ensembl:ENSP00000304283	F		Seeded From UniProt	complete
enables	GO:0003924	GTPase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001806	F		Seeded From UniProt	complete
enables	GO:0005525	GTP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001806 InterPro:IPR003578 InterPro:IPR005225	F		Seeded From UniProt	complete
involved_in	GO:0007264	small GTPase mediated signal transduction	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003578	P		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
enables	GO:0005525	GTP binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0342	F		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Paris, S et al. (2002) Analysis of the subcellular distribution of avian p95-APP2, an ARF-GAP orthologous to mammalian paxillin kinase linker. Int. J. Biochem. Cell Biol. 34 826-37 PubMed GONUTS page
↑ Malosio, ML et al. (1997) Differential expression of distinct members of Rho family GTP-binding proteins during neuronal development: identification of Rac1B, a new neural-specific member of the family. J. Neurosci. 17 6717-28 PubMed GONUTS page
↑ ^3.0 ^3.1 Albertinazzi, C et al. (1998) Overexpression of a neural-specific rho family GTPase, cRac1B, selectively induces enhanced neuritogenesis and neurite branching in primary neurons. J. Cell Biol. 142 815-25 PubMed GONUTS page

[PMID:11950598-1] Paris, S et al. (2002) Analysis of the subcellular distribution of avian p95-APP2, an ARF-GAP orthologous to mammalian paxillin kinase linker. Int. J. Biochem. Cell Biol. 34 826-37 PubMed GONUTS page

[PMID:9254684-2] Malosio, ML et al. (1997) Differential expression of distinct members of Rho family GTP-binding proteins during neuronal development: identification of Rac1B, a new neural-specific member of the family. J. Neurosci. 17 6717-28 PubMed GONUTS page

[PMID:9700168-3] 3.0 ^3.1 Albertinazzi, C et al. (1998) Overexpression of a neural-specific rho family GTPase, cRac1B, selectively induces enhanced neuritogenesis and neurite branching in primary neurons. J. Cell Biol. 142 815-25 PubMed GONUTS page

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CHICK:O93466

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